MIRA-1 | Tocris Bioscience 3362/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

MIRA-1

catalog :

3362/10

quantity :

10 mg (also 50 mg)

price :

134 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Saha M, Chen Y, Chen M, Chen G, Chang H. Small molecule MIRA-1 induces in vitro and in vivo anti-myeloma activity and synergizes with current anti-myeloma agents. Br J Cancer. 2014;110:2224-31 pubmed publisher

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

3362

SKU :

3362/10

product name :

MIRA-1

description :

Restores mutant p53 activity; proapoptotic

target :

Additional p53-related Compounds

unit size :

10 mg (also 50 mg)

category :

Small Molecules

storage :

Store at +4°C

observed molecular weight :

183.16

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

MIRA-1 is a restores wild-type conformation, function and DNA binding activity to mutant p53. Induces p53 transcriptional transactivation of p21, MDM2 and PUMA, and promotes tumor cell death by apoptosis in a mutant p53-dependent manner in vitro (IC50 = 10 M).

product keywords :

Restores mutant p53 activity proapoptotic Transcription Factors p53 3362,

extended description :

Restores mutant p53 activity; proapoptotic

chemical name text :

1-[(1-Oxopropoxy)methyl]-1H-pyrrole-2,5-dione

formula :

C8H9NO4

formula text :

C8H9NO4

cas num :

72835-26-8

USD :

148

USD 2025 :

134 USD

product details :

Restores mutant p53 activity; proapoptotic

more info or order :

Tocris Bioscience product webpage