JNJ 17203212 | Tocris Bioscience 3361/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

JNJ 17203212

catalog :

3361/10

quantity :

10 mg (also 50 mg)

price :

238 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Vijayvergiya V, Acharya S, Wilson S, Schmidt J. Measurement of Ensemble TRPV1 Ion Channel Currents Using Droplet Bilayers. PLoS ONE. 2015;10:e0141366 pubmed publisher
Kelly S, Chapman R, Woodhams S, Sagar D, Turner J, Burston J, et al. Increased function of pronociceptive TRPV1 at the level of the joint in a rat model of osteoarthritis pain. Ann Rheum Dis. 2015;74:252-9 pubmed publisher

image

image 1 :

Cat.No. 3361 - JNJ 17203212 C17H15F6N5O CAS No. 821768-06-3

product information

brand :

Tocris, a Bio-Techne Brand

catalog number base :

3361

SKU :

3361/10

product name :

JNJ 17203212

Description :

Reversible, competitive and potent TRPV1 antagonist

target :

TRPV Antagonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

419.32

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

JNJ 17203212 is a reversible, competitive and potent TRPV1 antagonist (pKi values are 6.5, 7.1 and 7.3 at rat, guinea pig and human TRPV1 respectively). Inhibits capsaicin- and H+-induced channel activation (pIC50 values are 6.32 and 7.23 respectively) and exhibits antitussive and analgesic activity in vivo .

extended description :

Reversible, competitive and potent TRPV1 antagonist

chemical name text :

4-[3-(Trifluoromethyl)-2-pyridinyl]-N-[5-(trifluoromethyl)-2-pyridinyl]-1-piperazinecarboxamide

formula :

C 17 H 15 F 6 N 5 O

formula text :

C17H15F6N5O

cas num :

821768-06-3

USD :

238 USD

product details :

Reversible, competitive and potent TRPV1 antagonist

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage