JNJ 28871063 hydrochloride | Tocris Bioscience 3352 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

JNJ 28871063 hydrochloride

catalog :

3352

quantity :

10 mg (also 50 mg)

price :

219 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

3352

SKU :

3352/10

product name :

JNJ 28871063 hydrochloride

description :

Potent ErbB receptor family inhibitor

target :

EGF Receptor Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

97%

observed molecular weight :

519.42

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective ErbB receptor family inhibitor (IC50 values are 21, 22 and 38 nM for ErbB4, EGFR and ErbB2 respectively). Displays potent growth inhibition of human cancer cell lines overexpressing ErbB2 in vitro (IC50 = 60 - 168 nM) and inhibits growth of human tumor xenografts in vivo . Brain penetrant and orally active.

catalog number base :

3352

product keywords :

Potent ErbB receptor family inhibitors inhibits Epidermal Growth Factors Receptors Her EGFR Receptor Tyrosine Kinases RTKs JNJ28871063 hydrochloride EGFR 3352,

extended description :

Potent ErbB receptor family inhibitor

chemical name text :

5E-4-Amino-6-(4-benzyloxy-3-chlorophenylamino)pyrimidine-5-carboxaldehyde N-(2-morpholin-4-ylethyl) oxime hydrochloride

formula :

C 24 H 27 ClN 6 O 3 .HCl

formula text :

C24H27ClN6O3.HCl

cas num :

944342-90-9

2020 USD :

214

2021 USD :

219 USD

storage :

Desiccate at +4°C

more info or order :

Tocris Bioscience product webpage