JNJ 28871063 hydrochloride | Tocris Bioscience 3352/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

JNJ 28871063 hydrochloride

catalog :

3352/10

quantity :

10 mg (also 50 mg)

price :

276 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 3352 - JNJ 28871063 hydrochloride C24H27ClN6O3.HCl CAS No. 944342-90-9

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

3352

SKU :

3352/10

product name :

JNJ 28871063 hydrochloride

description :

Potent ErbB receptor family inhibitor

target :

EGF Receptor Inhibitors

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

97%

storage :

Desiccate at +4°C

observed molecular weight :

519.42

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

JNJ 28871063 hydrochloride is a potent and selective ErbB receptor family inhibitor (IC50 values are 21, 22 and 38 nM for ErbB4, EGFR and ErbB2 respectively). Displays potent growth inhibition of human cancer cell lines overexpressing ErbB2 in vitro (IC50 = 60 - 168 nM) and inhibits growth of human tumor xenografts in vivo . Brain penetrant and orally active.

product keywords :

Potent ErbB receptor family inhibitors inhibits Epidermal Growth Factors Receptors Her EGFR Receptor Tyrosine Kinases RTKs JNJ28871063 hydrochloride EGFR 3352,

extended description :

Potent ErbB receptor family inhibitor

chemical name text :

5E-4-Amino-6-(4-benzyloxy-3-chlorophenylamino)pyrimidine-5-carboxaldehyde N-(2-morpholin-4-ylethyl) oxime hydrochloride

formula :

C24H27ClN6O3.HCl

formula text :

C24H27ClN6O3.HCl

cas num :

944342-90-9

USD :

273

USD 2025 :

276 USD

product details :

Potent ErbB receptor family inhibitor

more info or order :

Tocris Bioscience product webpage