LY 393558 | Tocris Bioscience 3350 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

LY 393558

catalog :

3350

quantity :

10 mg (also 50 mg)

price :

134 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

3350

SKU :

3350/10

product name :

LY 393558

description :

Dual 5-HT1B and 5-HT1D antagonist; also 5-HT re-uptake inhibitor

target :

5-HT1B Receptor Antagonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

97%

observed molecular weight :

546.68

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Dual 5-HT1B/1D receptor antagonist (pKB values are 9.05 and 8.98 respectively) and 5-HT re-uptake inhibitor (pIC50 = 8.48). Potently antagonizes terminal autoreceptor activity in vitro and increases extracellular 5-HT levels above those evoked by fluoxetine (Cat. No. 0927) in vivo . Also acts as an antagonist at 5-HT2A and 5-HT2B receptors (pKi values are 7.29 and 7.35 respectively).

catalog number base :

3350

product keywords :

LY393558 dual 5-HT1B 5-HT1D 5-HT1B/1D receptors antagonists serotonin reuptake uptake SERT inhibitors inhibits transporters 5-HT1 5-Hydroxytryptamine 5-HT1B Receptors 5-HT1D Receptors 5-HT Transporters 3350,

extended description :

Dual 5-HT1B and 5-HT1D antagonist; also 5-HT re-uptake inhibitor

chemical name text :

1-[2-[4-(6-Fluoro-1H-indol-3-yl)-3,6-dihydro-1(2H)-pyridinyl]ethyl]-3,4-dihydro-3-(1-methylethyl)-6-(methylsulfonyl)-1H-2,1,3-benzothiadiazine-2,2-dioxide

formula :

C 26 H 31 FN 4 O 4 S 2

formula text :

C26H31FN4O4S2

cas num :

271780-64-4

2020 USD :

131

2021 USD :

134 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage