product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
ATC 0175 hydrochloride
catalog :
3346
quantity :
10 mg (also 50 mg)
price :
220 USD
more info or order :
product information
brand :
Tocris
master code :
3346
SKU :
3346/10
product name :
ATC 0175 hydrochloride
description :
MCH1 antagonist; also 5-HT2B antagonist and 5-HT1A partial agonist
target :
Melanin-concentrating Hormone Receptor Antagonists
category :
Small Molecules
unit size :
10 mg (also 50 mg)
purity :
98%
observed molecular weight :
461.94
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Potent, selective and orally active melanin-concentrating hormone receptor 1 (MCH1) antagonist (IC50 values are 13.5 and 10000 nM for MCH1 and MCH2 receptors respectively). Exhibits anxiolytic and antidepressant activity in rodents. Also displays affinity for 5-HT2B and 5-HT1A receptors (IC50 values are 9.66 and 16.9 nM respectively).
catalog number base :
3346
product keywords :
MCH1 melanin concentrating hormone receptors 5-HT serotonin antagonists ATC0175 hydrochloride 5-HT2b 5-HT1a partial MCHR1 MCH1R Melanin-concentrating Hormone Receptors 5-HT2B Receptors 5-HT1A Receptors 3346,
extended description :
MCH1 antagonist; also 5-HT2B antagonist and 5-HT1A partial agonist
chemical name text :
N-[cis-4-[[4-(Dimethylamino)-2-quinazolinyl]amino]cyclohexyl]-3,4-difluorobenzamide hydrochloride
formula :
C 23 H 25 F 2 N 5 O.HCl
formula text :
C23H25F2N5O.HCl
cas num :
510733-97-8
2020 USD :
215
2021 USD :
220 USD
storage :
Store at +4°C
more info or order :
company information

Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com800-343-7475
headquarters: UK
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