SLV 320 | Tocris Bioscience 3344 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

SLV 320

catalog :

3344

quantity :

10 mg (also 50 mg)

price :

181 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Badders N, Korff A, Miranda H, Vuppala P, Smith R, Winborn B, et al. Selective modulation of the androgen receptor AF2 domain rescues degeneration in spinal bulbar muscular atrophy. Nat Med. 2018;24:427-437 pubmed publisher
Cheng R, Segala E, Robertson N, Deflorian F, DorÃ© A, Errey J, et al. Structures of Human A1 and A2A Adenosine Receptors with Xanthines Reveal Determinants of Selectivity. Structure. 2017;25:1275-1285.e4 pubmed publisher

product information

brand :

Tocris

master code :

3344

SKU :

3344/10

product name :

SLV 320

description :

Potent and selective A1 antagonist

target :

Adenosine A1 Receptor Antagonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

308.38

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective adenosine A1 receptor antagonist (Ki values are 1, 200, 398 and 3981 nM at human A1, A3, A2A and A2B receptors respectively). Suppresses cardiac fibrosis and attenuates albuminuria, without effect on blood pressure in animal models of chronic renal failure. Orally active.

catalog number base :

3344

product keywords :

Potent selective A1 antagonists Receptors adenosines SLV320 Adenosine A1 Receptors 3344,

extended description :

Potent and selective A1 antagonist

chemical name text :

trans-4-[(2-Phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclohexanol

formula :

C 18 H 20 N 4 O

formula text :

C18H20N4O

cas num :

251945-92-3

2020 USD :

175

2021 USD :

181 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage