ARL 17477 dihydrochloride | Tocris Bioscience 3319 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

ARL 17477 dihydrochloride

catalog :

3319

quantity :

10 mg (also 50 mg)

price :

166 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Grekov I, Pombinho A, Kobets T, Bartunek P, Lipoldová M. Calcium Ionophore, Calcimycin, Kills Leishmania Promastigotes by Activating Parasite Nitric Oxide Synthase. Biomed Res Int. 2017;2017:1309485 pubmed publisher

product information

brand :

Tocris

master code :

3319

SKU :

3319/10

product name :

ARL 17477 dihydrochloride

description :

Selective nNOS inhibitor

target :

nNOS Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

442.83

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Selective neuronal nitrogen oxide synthase (nNOS) inhibitor (IC50 values are 1 and 17 M for nNOS and endothelial NOS respectively). Reduces ischemic cell damage after middle cerebral artery (MCA) occlusion in rats. Displays a synergistic neuroprotective effect when combined with either an NMDA or AMPA receptor antagonist.

catalog number base :

3319

product keywords :

neuronal nitric oxide synthase nNOS inhibitors inhibits ARL17477 nNOS 3319,

extended description :

Selective nNOS inhibitor

chemical name text :

N-[4-[2-[[(3-Chlorophenyl)methyl]amino]ethyl]phenyl]-2-thiophenecarboxamide dihydrochloride

formula :

C 20 H 20 ClN 3 S.2HCl

formula text :

C20H20ClN3S.2HCl

cas num :

866914-87-6

2020 USD :

162

2021 USD :

166 USD

storage :

Desiccate at RT

more info or order :

Tocris Bioscience product webpage