Fluvastatin sodium | Tocris Bioscience 3309 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Fluvastatin sodium

catalog :

3309

quantity :

50 mg

price :

126 USD

more info or order :

Tocris Bioscience product webpage

citations: 5

Reference
Park Y, Wood G, Kastner D, Chae J. Pyrin inflammasome activation and RhoA signaling in the autoinflammatory diseases FMF and HIDS. Nat Immunol. 2016;17:914-21 pubmed publisher
Rojo Arreola L, Long T, Asarnow D, Suzuki B, Singh R, Caffrey C. Chemical and genetic validation of the statin drug target to treat the helminth disease, schistosomiasis. PLoS ONE. 2014;9:e87594 pubmed publisher
Li J, Fountain S. Fluvastatin suppresses native and recombinant human P2X4 receptor function. Purinergic Signal. 2012;8:311-6 pubmed publisher
Vainio P, Lehtinen L, Mirtti T, Hilvo M, Seppanen Laakso T, Virtanen J, et al. Phospholipase PLA2G7, associated with aggressive prostate cancer, promotes prostate cancer cell migration and invasion and is inhibited by statins. Oncotarget. 2011;2:1176-90 pubmed
Bergman P, Linde C, Pütsep K, Pohanka A, Normark S, Henriques Normark B, et al. Studies on the antibacterial effects of statins--in vitro and in vivo. PLoS ONE. 2011;6:e24394 pubmed publisher

product information

brand :

Tocris

master code :

3309

SKU :

3309/50

product name :

Fluvastatin sodium

description :

Potent HMG-CoA reductase inhibitor

target :

HMG-CoA Reductase Inhibitors

category :

Small Molecules

unit size :

50 mg

purity :

98%

observed molecular weight :

433.45

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Orally active, potent and competitive HMG-CoA reductase inhibitor (IC50 = 40 -100 nM at human liver microsomes). Inhibits vascular smooth muscle proliferation in vitro (IC50 = 70 nM) and exhibits antihypercholesterolemic and antioxidant activity in vivo .

catalog number base :

3309

product keywords :

HMG-CoA reductases inhibitors inhibits statins HMG-CoA Reductase 3309,

extended description :

Potent HMG-CoA reductase inhibitor

chemical name text :

( )-(3R*,5S*,6E)-7-[3-(4-Fluorophenyl)-1-(1-methyethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid sodium salt

formula :

C 24 H 25 FNNaO 4

formula text :

C24H25FNNaO4

cas num :

93957-55-2

2020 USD :

122

2021 USD :

126 USD

storage :

Desiccate at -20°C

more info or order :

Tocris Bioscience product webpage