AP 18 | Tocris Bioscience 3296 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

AP 18

catalog :

3296

quantity :

10 mg (also 50 mg)

price :

140 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Izzo A, Capasso R, Aviello G, Borrelli F, Romano B, Piscitelli F, et al. Inhibitory effect of cannabichromene, a major non-psychotropic cannabinoid extracted from Cannabis sativa, on inflammation-induced hypermotility in mice. Br J Pharmacol. 2012;166:1444-60 pubmed publisher
Capasso R, Aviello G, Romano B, Borrelli F, De Petrocellis L, Di Marzo V, et al. Modulation of mouse gastrointestinal motility by allyl isothiocyanate, a constituent of cruciferous vegetables (Brassicaceae): evidence for TRPA1-independent effects. Br J Pharmacol. 2012;165:1966-1977 pubmed publisher

product information

brand :

Tocris

master code :

3296

SKU :

3296/10

product name :

AP 18

description :

Reversible TRPA1 channel blocker

target :

TRPA1 Blockers

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

209.67

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Reversible TRPA1 channel blocker (IC50 values are 3.1 and 4.5 M at human and mouse TRPA1 respectively). Blocks cinnameldehyde-induced but not capsaicin-induced nociception and reverses mechanical hyperalgesia in vivo . Also blocks TRPA1 pore dilation (IC50 = 10.3 M for the inhibition of Yo-Pro uptake).

catalog number base :

3296

product keywords :

Reversible TRPA1 channel blockers Channels Transient Receptor Potential AP18 TRPA1 3296,

extended description :

Reversible TRPA1 channel blocker

chemical name text :

4-(4-Chlorophenyl)-3-methyl-3-buten-2-one oxime

formula :

C 11 H 12 ClNO

formula text :

C11H12ClNO

cas num :

55224-94-7

2020 USD :

135

2021 USD :

140 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage