Metyrapone | Tocris Bioscience 3292 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Metyrapone

catalog :

3292

quantity :

50 mg

price :

86 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Taves M, Plumb A, Korol A, Van Der Gugten J, Holmes D, Abraham N, et al. Lymphoid organs of neonatal and adult mice preferentially produce active glucocorticoids from metabolites, not precursors. Brain Behav Immun. 2016;57:271-281 pubmed publisher
RincÃ³n CortÃ©s M, Barr G, Mouly A, Shionoya K, NuÃ±ez B, Sullivan R. Enduring good memories of infant trauma: rescue of adult neurobehavioral deficits via amygdala serotonin and corticosterone interaction. Proc Natl Acad Sci U S A. 2015;112:881-6 pubmed publisher
Liu Z, Song C, Wang M, He Y, Xu X, Pan H, et al. Chronic stress impairs GABAergic control of amygdala through suppressing the tonic GABAA receptor currents. Mol Brain. 2014;7:32 pubmed publisher

product information

brand :

Tocris

master code :

3292

SKU :

3292/50

product name :

Metyrapone

description :

11- hydroxylase inhibitor

target :

Hydroxylase Inhibitors

category :

Small Molecules

unit size :

50 mg

purity :

99%

observed molecular weight :

226.27

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Cytochrome P450 inhibitor. Blocks glucocorticoid synthesis via inhibition of steroid 11- hydroxylase (CYP11B1) activity (IC50 = 7.83 M). Also inhibits CYP3A4 and cytochrome P450-mediated / -1 hydroxylase activity.

catalog number base :

3292

product keywords :

steroid 11- 11-beta hydroxylase inhibitors inhibits Cytochrome P450 CYP11B1 CYP3A4 omega/ω-1 omega-1 Hydroxylases Cytochrome P450 3292,

extended description :

11- hydroxylase inhibitor

chemical name text :

2-Methyl-1,2-di-3-pyridinyl-1-propanone

formula :

C 14 H 14 N 2 O

formula text :

C14H14N2O

cas num :

54-36-4

2020 USD :

2021 USD :

86 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage