(+/-)-LY 395756 | Tocris Bioscience 3272/10 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

(+/-)-LY 395756

catalog :

3272/10

quantity :

10 mg (also 50 mg)

price :

264 USD

citations: 2

Reference
Johnson K, Mateo Y, Lovinger D. Metabotropic glutamate receptor 2 inhibits thalamically-driven glutamate and dopamine release in the dorsal striatum. Neuropharmacology. 2017;117:114-123 pubmed publisher
Wang M, Li Y, Snyder M, Wang H, Li F, Gao W. Group II metabotropic glutamate receptor agonist LY379268 regulates AMPA receptor trafficking in prefrontal cortical neurons. PLoS ONE. 2013;8:e61787 pubmed publisher

product information

brand :

Tocris

master code :

3272

SKU :

3272/10

product name :

(+/-)-LY 395756

description :

Mixed mGlu2 agonist/ mGlu3 antagonist

target :

Glutamate Receptor Compounds

category :

Small Molecules

unit sizes :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

199.21

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

( )-LY 395756 is a selective metabotropic glutamate ligand for mGlu2 and mGlu3 receptors (Ki values are 0.165 M and 0.302 M respectively). Acts as an agonist at mGlu2 and antagonist at mGlu3. Analog of LY 354740 (Cat. No. 3246).

extended description :

Mixed mGlu2 agonist/ mGlu3 antagonist

chemical name text :

(1S,2S,4R,5R,6S)-rel-2-Amino-4-methylbicyclo[3.1.0]hexane-2,6-dicarboxylic acid

formula :

C 9 H 13 NO 4

formula text :

C9H13NO4

cas num :

852679-66-4

USD :

264 USD

product details :

Mixed mGlu2 agonist/ mGlu3 antagonist

storage :

Store at +4°C