GIT 27 | Tocris Bioscience 3270 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

GIT 27

catalog :

3270

quantity :

10 mg (also 50 mg)

price :

122 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Saurus P, Kuusela S, Lehtonen E, HyvÃ¶nen M, Ristola M, Fogarty C, et al. Podocyte apoptosis is prevented by blocking the Toll-like receptor pathway. Cell Death Dis. 2015;6:e1752 pubmed publisher

product information

brand :

Tocris

master code :

3270

SKU :

3270/10

product name :

GIT 27

description :

Immunomodulator; reduces production of pro-inflammatory cytokines

target :

Cytokine Compounds

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

205.21

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Orally active immunomodulatory agent that primarily targets macrophages. Inhibits TNF- secretion via interference of macrophage toll-like receptor (TLR) 4 and TLR 2/6 signaling pathway. Also reduces the secretion of pro-inflammatory cytokines IL1- , IL-10 and IFN- . Antidiabetogenic; prevents IL- and IFN- -induced pancreatic islet cell death in vitro .

catalog number base :

3270

product keywords :

Interfers TLR4 TLR2/6 signalling Immunomodulators reduces production pro-inflammatory cytokines Toll-like Receptors TNF- TNF-alpha Interleukins Tumor Necrosis Factor- Factor-alpha Cytokines Cytokine NF- B NF-kappaB Signaling Signalling GI Cytokines Toll-like Receptors 3270,

extended description :

Immunomodulator; reduces production of pro-inflammatory cytokines

chemical name text :

4,5-Dihydro-3-phenyl-5-isoxazoleacetic acid

formula :

C 11 H 11 NO 3

formula text :

C11H11NO3

cas num :

6501-72-0

2020 USD :

119

2021 USD :

122 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage