GIT 27 | Tocris Bioscience 3270/50 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

GIT 27

catalog :

3270/50

quantity :

50 mg

price :

545 USD

citations: 1

Reference
Saurus P, Kuusela S, Lehtonen E, HyvÃ¶nen M, Ristola M, Fogarty C, et al. Podocyte apoptosis is prevented by blocking the Toll-like receptor pathway. Cell Death Dis. 2015;6:e1752 pubmed publisher

product information

brand :

Tocris

master code :

3270

SKU :

3270/50

product name :

GIT 27

description :

Immunomodulator; reduces production of pro-inflammatory cytokines

target :

Cytokine Compounds

category :

Small Molecules

unit size :

50 mg

purity :

99%

observed molecular weight :

205.21

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

GIT 27 is an orally active immunomodulatory agent that primarily targets macrophages. Inhibits TNF- secretion via interference of macrophage toll-like receptor (TLR) 4 and TLR 2/6 signaling pathway. Also reduces the secretion of pro-inflammatory cytokines IL1- , IL-10 and IFN- . Antidiabetogenic; prevents IL- and IFN- -induced pancreatic islet cell death in vitro .

catalog number base :

3270

extended description :

Immunomodulator; reduces production of pro-inflammatory cytokines

chemical name text :

4,5-Dihydro-3-phenyl-5-isoxazoleacetic acid

formula :

C 11 H 11 NO 3

formula text :

C11H11NO3

cas num :

6501-72-0

USD 2021 :

510

USD 2022 :

545 USD

product details :

Immunomodulator; reduces production of pro-inflammatory cytokines

storage :

Store at +4°C