GIT 27 | Tocris Bioscience 3270/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

GIT 27

catalog :

3270/10

quantity :

10 mg (also 50 mg)

price :

154 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Saurus P, Kuusela S, Lehtonen E, HyvÃ¶nen M, Ristola M, Fogarty C, et al. Podocyte apoptosis is prevented by blocking the Toll-like receptor pathway. Cell Death Dis. 2015;6:e1752 pubmed publisher

product information

brand :

Tocris

catalog number base :

3270

SKU :

3270/10

product name :

GIT 27

units size :

10 mg (also 50 mg)

description :

Immunomodulator; reduces production of pro-inflammatory cytokines

target :

Cytokine Compounds

category :

Small Molecules

purity :

98%

observed molecular weight :

205.21

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

GIT 27 is an orally active immunomodulatory agent that primarily targets macrophages. Inhibits TNF- secretion via interference of macrophage toll-like receptor (TLR) 4 and TLR 2/6 signaling pathway. Also reduces the secretion of pro-inflammatory cytokines IL1- , IL-10 and IFN- . Antidiabetogenic; prevents IL- and IFN- -induced pancreatic islet cell death in vitro .

top caption :

Immunomodulator; reduces production of pro-inflammatory cytokines

extended description :

Immunomodulator; reduces production of pro-inflammatory cytokines

chemical name text :

4,5-Dihydro-3-phenyl-5-isoxazoleacetic acid

formula :

C11H11NO3

formula text :

C11H11NO3

cas num :

6501-72-0

USD :

154 USD

product details :

Immunomodulator; reduces production of pro-inflammatory cytokines

storage :

Store at +4Â°C

more info or order :

Tocris Bioscience product webpage