product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
Epirubicin hydrochloride
catalog :
3260
quantity :
10 mg
price :
212 USD
more info or order :
citations: 2
Reference
Kim D, Bynoe M. A2A adenosine receptor modulates drug efflux transporter P-glycoprotein at the blood-brain barrier. J Clin Invest. 2016;126:1717-33 pubmed publisher
Robinson T, Liu J, Vizeacoumar F, Sun T, MacLean N, Egan S, et al. RB1 status in triple negative breast cancer cells dictates response to radiation treatment and selective therapeutic drugs. PLoS ONE. 2013;8:e78641 pubmed publisher
product information
brand :
Tocris
master code :
3260
SKU :
3260/10
product name :
Epirubicin hydrochloride
description :
Inhibits DNA synthesis and function. Inhibits DNA topoisomerase II
target :
DNA, RNA and Protein Synthesis Inhibitors
category :
Small Molecules
unit size :
10 mg
purity :
96%
observed molecular weight :
579.98
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Antibiotic antitumor agent. Inhibits the synthesis and function of DNA (IC50 = 62.7 M in rat glioblastoma cell lines) and inhibits the relaxing property of topoisomerase II.
catalog number base :
3260
product keywords :
inhibitors inhibits DNA synthesis function topoisomerase II Isomerases antibiotics 4-Epidoxorubicin chemotherapeutics 4'-Epidoxorubicin DNA, RNA and Protein Synthesis DNA Topoisomerase Antibiotics 3260,
extended description :
Inhibits DNA synthesis and function. Inhibits DNA topoisomerase II
chemical name text :
(8S,10S)-10-[(3-Amino-2,3,6-trideoxy- -L-arabino-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,12-naphthacenedione hydrochloride
formula :
C 27 H 29 NO 11 .HCl
formula text :
C27H29NO11.HCl
cas num :
56390-09-1
2020 USD :
205
2021 USD :
212 USD
alt names :
4 -Epidoxorubicin
storage :
Desiccate at +4°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK