Mitomycin C | Tocris Bioscience 3258 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Mitomycin C

catalog :

3258

quantity :

10 mg

price :

164 USD

more info or order :

Tocris Bioscience product webpage

citations: 5

Reference
Stepp M, Pal Ghosh S, Tadvalkar G, Li L, Brooks S, Morasso M. Molecular basis of Mitomycin C enhanced corneal sensory nerve repair after debridement wounding. Sci Rep. 2018;8:16960 pubmed publisher
Kishinevsky S, Wang T, Rodina A, Chung S, Xu C, Philip J, et al. HSP90-incorporating chaperome networks as biosensor for disease-related pathways in patient-specific midbrain dopamine neurons. Nat Commun. 2018;9:4345 pubmed publisher
Woo J, Shimoni Y, Yang W, Subramaniam P, Iyer A, Nicoletti P, et al. Elucidating Compound Mechanism of Action by Network Perturbation Analysis. Cell. 2015;162:441-451 pubmed publisher
Reinhardt P, Glatza M, Hemmer K, Tsytsyura Y, Thiel C, Höing S, et al. Derivation and expansion using only small molecules of human neural progenitors for neurodegenerative disease modeling. PLoS ONE. 2013;8:e59252 pubmed publisher
Mayanagi T, Morita T, Hayashi K, Fukumoto K, Sobue K. Glucocorticoid receptor-mediated expression of caldesmon regulates cell migration via the reorganization of the actin cytoskeleton. J Biol Chem. 2008;283:31183-96 pubmed publisher

product information

brand :

Tocris

master code :

3258

SKU :

3258/10

product name :

Mitomycin C

description :

DNA cross-linking antitumor agent

target :

Apoptosis Inducer Compounds

category :

Small Molecules

unit size :

10 mg

purity :

98%

observed molecular weight :

334.33

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Antibiotic and antitumor agent. Covalently binds DNA forming intra- and interstrand crosslinks. Inhibits DNA synthesis. Also used for MEF/STO feeder layer preparation in stem cell culture.

catalog number base :

3258

product keywords :

inhibitors inhibits DNA synthesis cross-linking antitumor agents Apoptosis Inducer MitomycinC antibiotics chemotherapeutics stem cells feeder layers preparation culture Ametycine Apoptosis Inducers DNA, RNA and Protein Synthesis Antibiotics Stem Cell Signaling 3258,

extended description :

DNA cross-linking antitumor agent

chemical name text :

[1aS-(1a ,8 ,8a ,8b )]-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methylazirino[2 ,3 :3,4]pyrrolo[1,2-a]indole-4,7-dione

formula :

C 15 H 18 N 4 O 5

formula text :

C15H18N4O5

cas num :

50-07-7

2020 USD :

157

2021 USD :

164 USD

alt names :

Ametycine

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage