product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
Mitomycin C
catalog :
3258/2
quantity :
2 mg (also 10 mg)
price :
93 USD
more info or order :
citations: 5
Reference
Stepp M, Pal Ghosh S, Tadvalkar G, Li L, Brooks S, Morasso M. Molecular basis of Mitomycin C enhanced corneal sensory nerve repair after debridement wounding. Sci Rep. 2018;8:16960 pubmed publisher
Kishinevsky S, Wang T, Rodina A, Chung S, Xu C, Philip J, et al. HSP90-incorporating chaperome networks as biosensor for disease-related pathways in patient-specific midbrain dopamine neurons. Nat Commun. 2018;9:4345 pubmed publisher
Woo J, Shimoni Y, Yang W, Subramaniam P, Iyer A, Nicoletti P, et al. Elucidating Compound Mechanism of Action by Network Perturbation Analysis. Cell. 2015;162:441-451 pubmed publisher
Reinhardt P, Glatza M, Hemmer K, Tsytsyura Y, Thiel C, Höing S, et al. Derivation and expansion using only small molecules of human neural progenitors for neurodegenerative disease modeling. PLoS ONE. 2013;8:e59252 pubmed publisher
Mayanagi T, Morita T, Hayashi K, Fukumoto K, Sobue K. Glucocorticoid receptor-mediated expression of caldesmon regulates cell migration via the reorganization of the actin cytoskeleton. J Biol Chem. 2008;283:31183-96 pubmed publisher
image
image 1 :
Tocris Bioscience 3258/2 image 1
Cat.No. 3258 - Mitomycin C C15H18N4O5 CAS No. 50-07-7
product information
brand :
Tocris, a Bio-Techne Brand
catalog number base :
3258
SKU :
3258/2
product name :
Mitomycin C
Description :
DNA cross-linking antitumor agent
target :
Apoptosis Inducer Compounds
category :
Small Molecules
unit size :
2 mg (also 10 mg)
purity :
98%
observed molecular weight :
334.33
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Mitomycin C is an antibiotic and antitumor agent. Covalently binds DNA forming intra- and interstrand crosslinks. Inhibits DNA synthesis. Also used for MEF/STO feeder layer preparation in stem cell culture.
extended description :
DNA cross-linking antitumor agent
chemical name text :
[1aS-(1a ,8 ,8a ,8b )]-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methylazirino[2 ,3 :3,4]pyrrolo[1,2-a]indole-4,7-dione
formula :
C 15 H 18 N 4 O 5
formula text :
C15H18N4O5
cas num :
50-07-7
USD :
93 USD
product details :
DNA cross-linking antitumor agent
alt names :
Ametycine
storage :
Store at +4°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK