BMS 193885 | Tocris Bioscience 3242/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

BMS 193885

catalog :

3242/10

quantity :

10 mg (also 50 mg)

price :

347 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Acton D, Ren X, Di Costanzo S, Dalet A, Bourane S, Bertocchi I, et al. Spinal Neuropeptide Y1 Receptor-Expressing Neurons Form an Essential Excitatory Pathway for Mechanical Itch. Cell Rep. 2019;28:625-639.e6 pubmed publisher
Kawabe T, Kawabe K, Sapru H. Cardiovascular responses to chemical stimulation of the hypothalamic arcuate nucleus in the rat: role of the hypothalamic paraventricular nucleus. PLoS ONE. 2012;7:e45180 pubmed publisher

product information

brand :

Tocris

catalog number base :

3242

SKU :

3242/10

product name :

BMS 193885

units size :

10 mg (also 50 mg)

description :

Potent, competitive NPY Y1 receptor antagonist

target :

NPY Receptor Antagonists

category :

Small Molecules

purity :

98%

observed molecular weight :

680.79

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

BMS 193885 is a potent, competitive neuropeptide (NPY) Y1 antagonist (Ki = 3.3 nM, IC50 = 5.9 nM) that displays 47, 100, 160, 160 and 160-fold selectivity over 1, 1, Y2, Y4 and Y5 receptors respectively. Reduces food intake and body weight via central Y1 inhibition and is brain penetrant.

top caption :

Potent, competitive NPY Y1 receptor antagonist

extended description :

Potent, competitive NPY Y1 receptor antagonist

chemical name text :

1,4-Dihydro-4-[3-[[[[3-[4-(3-methoxyphenyl)-1-piperidinyl]propyl]amino]carbonyl]amino]phenyl]-2,6-dimethyl-3,5-pyridinedicarboxylic acid 3,5-dimethyl ester L-Lactate

formula :

C33H42N4O6.C3H6O3

formula text :

C33H42N4O6.C3H6O3

cas num :

679839-66-8

USD :

347 USD

product details :

Potent, competitive NPY Y1 receptor antagonist

storage :

Desiccate at RT

more info or order :

Tocris Bioscience product webpage