TCS PrP Inhibitor 13 | Tocris Bioscience 3238/10 product information

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product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

TCS PrP Inhibitor 13

catalog :

3238/10

quantity :

10 mg (also 50 mg)

price :

144 USD

citations: 2

Reference
Safavifar F, Saadat F, Jalali S, Khoramizadeh M. Augmented cAMP Signaling by Co-Administration of Resveratrol and Curcumin: A Cellular Biosensor Kinetic Assessment. Iran J Public Health. 2019;48:1310-1316 pubmed
Provenzano L, Ryan Y, Hilton D, Lyons Rimmer J, Dave F, Maze E, et al. Cellular prion protein (PrPC) in the development of Merlin-deficient tumours. Oncogene. 2017;36:6132-6142 pubmed publisher

product information

brand :

Tocris

MasterCode :

3238

SKU :

3238/10

product name :

TCS PrP Inhibitor 13

unit sizes :

10 mg (also 50 mg)

description :

Antiprion agent; inhibits PrPSc accumulation

target :

Neuronal Metabolism Peptides and Compounds

category :

Small Molecules

purity :

98%

observed molecular weight :

281.27

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

TCS PrP Inhibitor 13 is an antiprion agent. Potently inhibits protease-resistant prion protein (PrP-res) accumulation in two types of prion-infected mouse neuroblastoma (N2a) cell lines (IC50 = 3 nM). Also reduces PrP expression and decreases proliferation and survival in schwannoma cell lines.

extended description :

Antiprion agent; inhibits PrPSc accumulation

chemical name text :

2,4-Dihydro-5-(4-nitrophenyl)-2-phenyl-3H-pyrazol-3-one

formula :

C 15 H 11 N 3 O 3

formula text :

C15H11N3O3

cas num :

34320-83-7

USD :

144 USD

product details :

Antiprion agent; inhibits PrPSc accumulation

storage :

Store at +4°C