TCS JNK 6o | Tocris Bioscience 3222/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

TCS JNK 6o

catalog :

3222/10

quantity :

10 mg (also 50 mg)

price :

289 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Xiao X, Lai W, Xie H, Liu Y, Guo W, Liu Y, et al. Targeting JNK pathway promotes human hematopoietic stem cell expansion. Cell Discov. 2019;5:2 pubmed publisher
Souvannaseng L, Hun L, Baker H, Klyver J, Wang B, Pakpour N, et al. Inhibition of JNK signaling in the Asian malaria vector Anopheles stephensi extends mosquito longevity and improves resistance to Plasmodium falciparum infection. PLoS Pathog. 2018;14:e1007418 pubmed publisher
Yang J, Ryan D, Wang W, Tsang J, Lan G, Masaki H, et al. Establishment of mouse expanded potential stem cells. Nature. 2017;550:393-397 pubmed publisher

product information

brand :

Tocris, a Bio-Techne Brand

catalog number base :

3222

SKU :

3222/10

product name :

TCS JNK 6o

Description :

Selective JNK inhibitor

target :

JNK/c-jun Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

356.38

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

TCS JNK 6o is an ATP-competitive c-Jun N-terminal kinase (JNK) inhibitor (IC50 values are 2, 4 and 52 nM for JNK1, JNK2 and JNK3 respectively). Displays 1000 fold selectivity over other kinases, including ERK2 and p38. Inhibits c-Jun phosphorylation (EC50 = 920 nM) and prevents collagen-induced platelet aggregation in vitro .

extended description :

Selective JNK inhibitor

chemical name text :

N-(4-Amino-5-cyano-6-ethoxy-2-pyridinyl)-2,5-dimethoxybenzeneacetamide

formula :

C 18 H 20 N 4 O 4

formula text :

C18H20N4O4

cas num :

894804-07-0

USD :

289 USD

product details :

Selective JNK inhibitor

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage