ShK-Dap22 | Tocris Bioscience 3220 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

ShK-Dap22

catalog :

3220

quantity :

100 ug

price :

293 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

3220

SKU :

3220/100U

product name :

ShK-Dap22

description :

Extremely potent and selective KV1.3 blocker; suppresses T cell activation in vitro

target :

Voltage-gated Potassium Channel Blockers

category :

Peptides

unit size :

100 ug

observed molecular weight :

4012.7

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=peptides

details of functionality :

Extremely potent KV1.3 channel blocker (Kd = 23 pM for mKV1.3 currents). Selective for KV1.3 over other mammalian potassium channels (IC50 values are 23, 1800, 10500, 37000 and 39000 pM for mKV1.3, mKV1.1, hKV1.6, mKV1.4 and rKV1.2 respectively, and 100000 pM for hKV1.5, mKV1.7, hKV3.1, rKV3.4 and hKCa4). Suppresses T cell activation in vitro (IC50 500 pM).

catalog number base :

3220

product keywords :

toxins potassium channels Kv1.3 potent selective blockers inhibitors inhibits immunosuppressives T cells venoms Voltage-Gated Potassium Channels 3220,

extended description :

Extremely potent and selective KV1.3 blocker; suppresses T cell activation in vitro

formula :

C 166 H 268 N 54 O 48 S 7

formula text :

C166H268N54O48S7

cas num :

220384-25-8

2020 USD :

284

2021 USD :

293 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage