ShK-Dap22 | Tocris Bioscience 3220/100U product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

ShK-Dap22

catalog :

3220/100U

quantity :

100 ug

price :

364 USD

product information

brand :

Tocris, a Bio-Techne Brand

catalog number base :

3220

SKU :

3220/100U

product name :

ShK-Dap22

Description :

Extremely potent and selective KV1.3 blocker; suppresses T cell activation in vitro

target :

Voltage-gated Potassium Channel Blockers

category :

Peptides

unit size :

100 ug

purity :

95%

observed molecular weight :

4012.7

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=peptides

details of functionality :

ShK-Dap22 is an extremely potent KV1.3 channel blocker (Kd = 23 pM for mKV1.3 currents). Selective for KV1.3 over other mammalian potassium channels (IC50 values are 23, 1800, 10500, 37000 and 39000 pM for mKV1.3, mKV1.1, hKV1.6, mKV1.4 and rKV1.2 respectively, and 100000 pM for hKV1.5, mKV1.7, hKV3.1, rKV3.4 and hKCa4). Suppresses T cell activation in vitro (IC50 500 pM).

extended description :

Extremely potent and selective KV1.3 blocker; suppresses T cell activation in vitro

formula :

C 166 H 268 N 54 O 48 S 7

formula text :

C166H268N54O48S7

cas num :

220384-25-8

USD :

364 USD

product details :

Extremely potent and selective KV1.3 blocker; suppresses T cell activation in vitro

storage :

Store at -20°C