Kifunensine | Tocris Bioscience 3207/1 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Kifunensine

catalog :

3207/1

quantity :

1 mg

price :

188 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Elegheert J, Behiels E, Bishop B, Scott S, Woolley R, Griffiths S, et al. Lentiviral transduction of mammalian cells for fast, scalable and high-level production of soluble and membrane proteins. Nat Protoc. 2018;13:2991-3017 pubmed publisher
Nguyen H, Madani N, Ding H, Elder E, Princiotto A, Gu C, et al. Evaluation of the contribution of the transmembrane region to the ectodomain conformation of the human immunodeficiency virus (HIV-1) envelope glycoprotein. Virol J. 2017;14:33 pubmed publisher

product information

brand :

Tocris

catalog number base :

3207

SKU :

3207/1

product name :

Kifunensine

units size :

1 mg

description :

Inhibitor of class I -mannosidases

target :

Glycosylase Inhibitors

category :

Small Molecules

observed molecular weight :

232.19

url print :

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review stars :

details of functionality :

Kifunensine is an inhibitor of class I -mannosidases that inhibits glycoprotein processing. Kifunensine inhibits human endoplasmic reticulum -1,2-mannosidase I and Golgi Class I mannosidases IA, IB and IC with Ki values of 130 and 23 nM respectively. Kifunensine disrupts normal trafficking of the GLUT1 transporter, leading to decreased glucose uptake in human renal epithelial cells. Kifunensine impaires tumour cell aggregation in human ovarian cancer cells in vitro .

top caption :

Inhibitor of class I -mannosidases

extended description :

Inhibitor of class I -mannosidases

chemical name text :

(5R,6R,7S,8R,8aS)-Hexahydro-6,7,8-trihydroxy-5-(hydroxymethyl)-imidazo[1,2-a]pyridine-2,3-dione

formula :

C8H12N2O6

formula text :

C8H12N2O6

cas num :

109944-15-2

USD :

188 USD

product details :

Inhibitor of class I -mannosidases

storage :

Store at -20Â°C

more info or order :

Tocris Bioscience product webpage