Echistatin, alpha1 isoform | Tocris Bioscience 3202 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Echistatin, alpha1 isoform

catalog :

3202

quantity :

100 ug

price :

360 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Lin Y, Rao J, Zha X, Xu H. Angiopoietin-like 3 induces podocyte F-actin rearrangement through integrin ?(V)??/FAK/PI3K pathway-mediated Rac1 activation. Biomed Res Int. 2013;2013:135608 pubmed publisher
Schrader J, Gordon Walker T, Aucott R, van Deemter M, Quaas A, Walsh S, et al. Matrix stiffness modulates proliferation, chemotherapeutic response, and dormancy in hepatocellular carcinoma cells. Hepatology. 2011;53:1192-205 pubmed publisher

product information

brand :

Tocris

master code :

3202

SKU :

3202/100U

product name :

Echistatin, alpha1 isoform

description :

V 3 and glycoprotein IIb/IIIa (integrin IIb 3) inhibitor

target :

Integrin Receptor Inhibitors

category :

Peptides

unit size :

100 ug

observed molecular weight :

5417.1

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=peptides

details of functionality :

Potent irreversible V 3 integrin antagonist (Ki = 0.27 nM). Disrupts attachment of osteoclasts to bone and inhibits bone reabsorption (IC50 = 0.1 nM). Prevents ADP-induced platelet aggregation via inhibition of glycoprotein IIb/IIIa (GpIIb/IIIa, IIb 3) receptors (IC50 = 30 nM) in vitro .

catalog number base :

3202

product keywords :

V 3 alphaV 3 beta3 glycoprotein IIb/IIIa IIb 3 alphaIIb 3 inhibitors inhibits Integrin Receptors Adhesion Molecules Echistatin alpha1 isoform Echistatina1 alphavbeta3 Cell Adhesion Molecules Integrins 3202,

extended description :

V 3 and glycoprotein IIb/IIIa (integrin IIb 3) inhibitor

formula :

C 217 H 341 N 71 O 74 S 9

formula text :

C217H341N71O74S9

cas num :

154303-05-6

2020 USD :

349

2021 USD :

360 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage