Echistatin, alpha1 isoform | Tocris Bioscience 3202/100U product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Echistatin, alpha1 isoform

catalog :

3202/100U

quantity :

100 ug

price :

417 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Lin Y, Rao J, Zha X, Xu H. Angiopoietin-like 3 induces podocyte F-actin rearrangement through integrin ?(V)??/FAK/PI3K pathway-mediated Rac1 activation. Biomed Res Int. 2013;2013:135608 pubmed publisher
Schrader J, Gordon Walker T, Aucott R, van Deemter M, Quaas A, Walsh S, et al. Matrix stiffness modulates proliferation, chemotherapeutic response, and dormancy in hepatocellular carcinoma cells. Hepatology. 2011;53:1192-205 pubmed publisher

product information

brand :

Tocris

master code :

3202

SKU :

3202/100U

rank :

0.061

product name :

Echistatin, alpha1 isoform

description :

V 3 and glycoprotein IIb/IIIa (integrin IIb 3) inhibitor

target :

Integrin Receptor Inhibitors

category :

Peptides

sizes available :

100 ug

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=peptides

details of functionality :

Echistatin, 1 isoform is a potent irreversible V 3 integrin antagonist (Ki = 0.27 nM). Disrupts attachment of osteoclasts to bone and inhibits bone reabsorption (IC50 = 0.1 nM). Prevents ADP-induced platelet aggregation via inhibition of glycoprotein IIb/IIIa (GpIIb/IIIa, IIb 3) receptors (IC50 = 30 nM) in vitro .

extended description :

V 3 and glycoprotein IIb/IIIa (integrin IIb 3) inhibitor

formula :

C 217 H 341 N 71 O 74 S 9

formula text :

C217H341N71O74S9

cas num :

154303-05-6

USD :

417 USD

product details :

V 3 and glycoprotein IIb/IIIa (integrin IIb 3) inhibitor

storage :

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage