product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
PSB 603
catalog :
3198/10
quantity :
10 mg (also 50 mg)
price :
277 USD
more info or order :
citations: 6
Reference
Kang H, Shih Y, Nakasaki M, Kabra H, Varghese S. Small molecule-driven direct conversion of human pluripotent stem cells into functional osteoblasts. Sci Adv. 2016;2:e1600691 pubmed publisher
Rao V, Shih Y, Kang H, Kabra H, Varghese S. Adenosine Signaling Mediates Osteogenic Differentiation of Human Embryonic Stem Cells on Mineralized Matrices. Front Bioeng Biotechnol. 2015;3:185 pubmed publisher
Schneider G, Glaser T, Lameu C, Abdelbaset Ismail A, Sellers Z, Moniuszko M, et al. Extracellular nucleotides as novel, underappreciated pro-metastatic factors that stimulate purinergic signaling in human lung cancer cells. Mol Cancer. 2015;14:201 pubmed publisher
Stoddart L, Johnstone E, Wheal A, Goulding J, Robers M, Machleidt T, et al. Application of BRET to monitor ligand binding to GPCRs. Nat Methods. 2015;12:661-663 pubmed publisher
Long J, Schoonen P, Graczyk D, O Prey J, Ryan K. p73 engages A2B receptor signalling to prime cancer cells to chemotherapy-induced death. Oncogene. 2015;34:5152-62 pubmed publisher
Ham M, Mizumori M, Watanabe C, Wang J, Inoue T, Nakano T, et al. Endogenous luminal surface adenosine signaling regulates duodenal bicarbonate secretion in rats. J Pharmacol Exp Ther. 2010;335:607-13 pubmed publisher
product information
brand :
Tocris, a Bio-Techne brand
catalog number base :
3198
SKU :
3198/10
product name :
PSB 603
description :
Highly selective A2B antagonist
target :
Adenosine A2b Receptor Antagonists
unit size :
10 mg (also 50 mg)
category :
Small Molecules
purity :
98%
storage :
Store at +4°C
observed molecular weight :
529.01
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
PSB 603 is an adenosine A2B receptor antagonist that displays 17000-fold selectivity over other adenosine receptors (Ki values are 0.553, 10000, 10000 and 10000 nM for A2B, A1, A2A and A3 receptors respectively).
product keywords :
selective A2B antagonists Receptors adenosines PSB603 Adenosine A2B Receptors 3198,
extended description :
Highly selective A2B antagonist
chemical name text :
8-[4-[4-(4-Chlorophenzyl)piperazide-1-sulfonyl)phenyl]]-1-propylxanthine
formula :
C24H25ClN6O4S
formula text :
C24H25ClN6O4S
cas num :
1092351-10-4
USD :
268
USD 2025 :
277 USD
product details :
Highly selective A2B antagonist
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK