Polygodial | Tocris Bioscience 3197/10 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Polygodial

catalog :

3197/10

quantity :

10 mg (also 50 mg)

price :

228 USD

citations: 2

Reference
Silverman H, Tynan A, Hepler T, Chang E, Gunasekaran M, Li J, et al. Transient Receptor Potential Ankyrin-1-expressing vagus nerve fibers mediate IL-1β induced hypothermia and reflex anti-inflammatory responses. Mol Med. 2023;29:4 pubmed publisher
Shi H, Liu C, Ding L, Zheng Y, Fei X, Lu L, et al. Alterations in serotonin, transient receptor potential channels and protease-activated receptors in rats with irritable bowel syndrome attenuated by Shugan decoction. World J Gastroenterol. 2015;21:4852-63 pubmed publisher

product information

brand :

Tocris

master code :

3197

SKU :

3197/10

product name :

Polygodial

unit size :

10 mg (also 50 mg)

seo description :

TRPA1 channel activator; analgesic and antifungal

target :

TRPA1 Activators

category :

Small Molecules

purity :

97%

observed molecular weight :

234.33

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Polygodial is a TRPA1 channel activator (EC50 = 400 nM) that is selective against TRPV1, TRPV2, TRPV3, TRPV4 and TRPM8 channels. Acts as an analgesic via desensitization of sensory neurons. Also exhibits antifungal activity via inhibition of mitochondrial ATPase.

top caption :

TRPA1 channel activator; analgesic and antifungal

extended description :

TRPA1 channel activator; analgesic and antifungal

chemical name text :

(1R,4aS,8aS)-1,4,4a,5,6,7,8,8a-Octahydro-5,5,8a-trimethyl-1,2-naphthalenedicarboxaldehyde

formula :

C15H22O2

formula text :

C15H22O2

cas num :

6754-20-7

USD :

228 USD

product details :

TRPA1 channel activator; analgesic and antifungal

storage :

Store at -20░C