product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
BIO
catalog :
3194
quantity :
10 mg (also 50 mg)
price :
184 USD
more info or order :
citations: 18
Reference |
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Efthymiou A, Steiner J, Pavan W, Wincovitch S, Larson D, Porter F, et al. Rescue of an in vitro neuron phenotype identified in Niemann-Pick disease, type C1 induced pluripotent stem cell-derived neurons by modulating the WNT pathway and calcium signaling. Stem Cells Transl Med. 2015;4:230-8 pubmed publisher
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product information
brand :
Tocris
master code :
3194
SKU :
3194/10
product name :
BIO
description :
Potent GSK-3 inhibitor; also inhibits cdks
target :
GSK-3 Inhibitors
category :
Small Molecules
unit size :
10 mg (also 50 mg)
purity :
98%
observed molecular weight :
356.17
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Potent ATP-competitive glycogen synthase kinase-3 (GSK-3) inhibitor (IC50 = 5 nM). Also inhibits cyclin-dependent kinases (cdks; IC50 values are in vitro ; also promotes proliferation and dedifferentiation in cardiomyocytes. . Negative Control also available.
catalog number base :
3194
product keywords :
Potent selective GSK-3 inhibitors inhibits Glycogen Synthase Kinases 3 Carbohydrate Metabolism stem cells 6BIO Glycogen Synthase Kinase 3 Glycogen Synthase Kinase Stem Cell Proliferation Stem Cell Signaling Cyclin-dependent Kinase 3194,
extended description :
Potent GSK-3 inhibitor; also inhibits cdks
chemical name text :
(2 Z,3 E)-6-Bromoindirubin-3 -oxime
formula :
C 16 H 10 BrN 3 O 2
formula text :
C16H10BrN3O2
cas num :
667463-62-9
2020 USD :
176
2021 USD :
184 USD
alt names :
6BIO
storage :
Store at +4°C
more info or order :
company information

Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com800-343-7475
headquarters: UK
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