Camostat mesylate | Tocris Bioscience 3193 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Camostat mesylate

catalog :

3193

quantity :

10 mg (also 50 mg)

price :

62 USD

more info or order :

Tocris Bioscience product webpage

citations: 6

Reference
Matsuyama S, Shirato K, Kawase M, Terada Y, Kawachi K, Fukushi S, et al. Middle East Respiratory Syndrome Coronavirus Spike Protein Is Not Activated Directly by Cellular Furin during Viral Entry into Target Cells. J Virol. 2018;92: pubmed publisher
Shirato K, Kanou K, Kawase M, Matsuyama S. Clinical Isolates of Human Coronavirus 229E Bypass the Endosome for Cell Entry. J Virol. 2017;91: pubmed publisher
Shirato K, Kawase M, Matsuyama S. Middle East respiratory syndrome coronavirus infection mediated by the transmembrane serine protease TMPRSS2. J Virol. 2013;87:12552-61 pubmed publisher
Gamble J, Kenny S, Dockray G. Plasminogen activator inhibitor (PAI)-1 suppresses inhibition of gastric emptying by cholecystokinin (CCK) in mice. Regul Pept. 2013;185:9-13 pubmed publisher
Bertram S, Dijkman R, Habjan M, Heurich A, Gierer S, Glowacka I, et al. TMPRSS2 activates the human coronavirus 229E for cathepsin-independent host cell entry and is expressed in viral target cells in the respiratory epithelium. J Virol. 2013;87:6150-60 pubmed publisher
Kawase M, Shirato K, van der Hoek L, Taguchi F, Matsuyama S. Simultaneous treatment of human bronchial epithelial cells with serine and cysteine protease inhibitors prevents severe acute respiratory syndrome coronavirus entry. J Virol. 2012;86:6537-45 pubmed publisher

product information

brand :

Tocris

master code :

3193

SKU :

3193/10

product name :

Camostat mesylate

description :

Orally active protease inhibitor; inhibits entry of SARS-Cov-2 into lung cells

target :

Additional Synthetic Protease Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

494.52

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Orally active protease inhibitor. Inhibits trypsin and various inflammatory proteases including plasmin, kallikrein and thrombin. Suppresses pancreatitis-induced pain in rats following oral administration. Also inhibits transmembrane serine protease TMPRSS2 and partially blocks entry of SARS-Cov-2 (COVID-19) into lung cells in vitro . . Tocris products are for biomedical research use only. They are not intended for human or veterinary use.

catalog number base :

3193

product keywords :

Orally active proteases inhibitors inhibits Proteinases trypsin plasmin kallikrein thrombin serine protease TMPRSS2 SARS-Cov-2 COVID-19 coronaviruses severe acute respiratory syndrome Other Proteases COVID-19 TMPRSS2 Coronavirus 3193, corona virus, betacoronavirus

extended description :

Orally active protease inhibitor; inhibits entry of SARS-Cov-2 into lung cells

chemical name text :

4-[[4-[(Aminoiminomethyl)amino]benzoyl]oxy]benzeneacetic acid 2-(dimethylamino)-2-oxoethyl ester methanesulfonate

formula :

C 20 H 22 N 4 O 5 .CH 3 SO 3 H

formula text :

C20H22N4O5.CH3SO3H

cas num :

59721-29-8

2020 USD :

2021 USD :

62 USD

storage :

Desiccate at RT

more info or order :

Tocris Bioscience product webpage