KM 11060 | Tocris Bioscience 3143 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

KM 11060

catalog :

3143

quantity :

10 mg (also 50 mg)

price :

116 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Zhao C, Su E, Yang X, Gao Z, Li L, Wu H, et al. Important role of platelets in modulating endotoxin-induced lung inflammation in CFTR-deficient mice. PLoS ONE. 2013;8:e82683 pubmed publisher

product information

brand :

Tocris

master code :

3143

SKU :

3143/10

product name :

KM 11060

description :

Corrects F508del-CFTR trafficking

target :

Other CFTR Compounds

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

422.33

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Corrects F508del-CFTR trafficking; increases the amount of functional CFTR at the plasma membrane (~75%). Shown to inhibit PDE5 activity.

catalog number base :

3143

product keywords :

Corrects F508del-CFTR trafficking Cl- Channels VSAC Chloride KM11060 pharmacochaperones CFTR 3143,

extended description :

Corrects F508del-CFTR trafficking

chemical name text :

7-Chloro-4-[4-[4-chlorophenyl)sulfonyl]-1-piperazinyl]quinoline

formula :

C 19 H 17 Cl 2 N 3 O 2 S

formula text :

C19H17Cl2N3O2S

cas num :

774549-97-2

2020 USD :

128

2021 USD :

116 USD

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage