VU 10010 | Tocris Bioscience 3141 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

VU 10010

catalog :

3141

quantity :

10 mg (also 50 mg)

price :

197 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Bell L, Bell K, McQuiston A. Acetylcholine release in mouse hippocampal CA1 preferentially activates inhibitory-selective interneurons via Î±4Î²2* nicotinic receptor activation. Front Cell Neurosci. 2015;9:115 pubmed publisher

product information

brand :

Tocris

master code :

3141

SKU :

3141/10

product name :

VU 10010

description :

Selective positive allosteric modulator of M4 receptors

target :

mAChR M4 Modulators

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

345.85

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Selective allosteric potentiator of M4 acetylcholine receptors (EC50 values are 33 and 0.7 nM for ACh in the absence and presence of VU10010 respectively). Binds to an allosteric site on the receptor increasing affinity for ACh and coupling to G-proteins.

catalog number base :

3141

product keywords :

Selective allosteric potentiator M4 receptors Muscarinic Receptors Acetylcholine ACh VU10010 M4 PAM M4 Receptors 3141,

extended description :

Selective positive allosteric modulator of M4 receptors

chemical name text :

3-Amino-N-[(4-chlorophenyl)methyl]-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide

formula :

C 17 H 16 ClN 3 OS

formula text :

C17H16ClN3OS

cas num :

633283-39-3

2020 USD :

193

2021 USD :

197 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage