VU 10010 | Tocris Bioscience 3141/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

VU 10010

catalog :

3141/10

quantity :

10 mg (also 50 mg)

price :

247 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Bell L, Bell K, McQuiston A. Acetylcholine release in mouse hippocampal CA1 preferentially activates inhibitory-selective interneurons via Î±4Î²2* nicotinic receptor activation. Front Cell Neurosci. 2015;9:115 pubmed publisher

product information

brand :

Tocris

catalog number base :

3141

SKU :

3141/10

product name :

VU 10010

units size :

10 mg (also 50 mg)

description :

Selective positive allosteric modulator of M4 receptors

target :

mAChR M4 Modulators

category :

Small Molecules

purity :

98%

observed molecular weight :

345.85

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

VU 10010 is a selective allosteric potentiator of M4 acetylcholine receptors (EC50 values are 33 and 0.7 nM for ACh in the absence and presence of VU10010 respectively). Binds to an allosteric site on the receptor increasing affinity for ACh and coupling to G-proteins.

top caption :

Selective positive allosteric modulator of M4 receptors

extended description :

Selective positive allosteric modulator of M4 receptors

chemical name text :

3-Amino-N-[(4-chlorophenyl)methyl]-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide

formula :

C17H16ClN3OS

formula text :

C17H16ClN3OS

cas num :

633283-39-3

USD :

247 USD

product details :

Selective positive allosteric modulator of M4 receptors

storage :

Store at +4Â°C

more info or order :

Tocris Bioscience product webpage