Ranolazine dihydrochloride | Tocris Bioscience 3118 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Ranolazine dihydrochloride

catalog :

3118

quantity :

50 mg

price :

129 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Carstensen H, Hesselkilde E, Haugaard M, Flethøj M, Carlson J, Pehrson S, et al. Effects of dofetilide and ranolazine on atrial fibrillatory rate in a horse model of acutely induced atrial fibrillation. J Cardiovasc Electrophysiol. 2019;30:596-606 pubmed publisher
McKeithan W, Savchenko A, YU M, Cerignoli F, Bruyneel A, Price J, et al. An Automated Platform for Assessment of Congenital and Drug-Induced Arrhythmia with hiPSC-Derived Cardiomyocytes. Front Physiol. 2017;8:766 pubmed publisher
Park Y, Johnston D, Gray R. Slowly inactivating component of Na+ current in peri-somatic region of hippocampal CA1 pyramidal neurons. J Neurophysiol. 2013;109:1378-90 pubmed publisher

product information

brand :

Tocris

master code :

3118

SKU :

3118/50

product name :

Ranolazine dihydrochloride

description :

Antianginal, activates pyruvate dehydrogenase

target :

Dehydrogenase Activators

category :

Small Molecules

unit size :

50 mg

purity :

98%

observed molecular weight :

500.46

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Antianginal agent with antiarrhythmic properties that acts as a partial fatty acid oxidation inhibitor. Activates pyruvate dehydrogenase in ischemic myocytes to promote glucose oxidation, switching substrate utilization from fatty acids to glucose. Also shown to inhibit late INa and IKr currents.

catalog number base :

3118

product keywords :

Anti-anginal activates pyruvate dehydrogenase anti-arrhythmic agent activators Enzyme Substrates RS43285 RS 43285 Other Dehydrogenases Enzyme Substrates/ Activators Miscellaneous Compounds 3118,

extended description :

Antianginal, activates pyruvate dehydrogenase

chemical name text :

N-(2,6-Dimethylphenyl)-4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]-1-piperazineacetamide dihydrochloride

formula :

C 24 H 33 N 3 O 4 .2HCl

formula text :

C24H33N3O4.2HCl

cas num :

95635-56-6

2020 USD :

124

2021 USD :

129 USD

alt names :

RS 43285

storage :

Desiccate at RT

more info or order :

Tocris Bioscience product webpage