Miglustat hydrochloride | Tocris Bioscience 3117 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Miglustat hydrochloride

catalog :

3117

quantity :

10 mg

price :

227 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Huang W, Tsai C, Chen C, Chen T, Chen Y, Lin Y, et al. Glucosylceramide synthase inhibitor PDMP sensitizes chronic myeloid leukemia T315I mutant to Bcr-Abl inhibitor and cooperatively induces glycogen synthase kinase-3-regulated apoptosis. FASEB J. 2011;25:3661-73 pubmed publisher

product information

brand :

Tocris

master code :

3117

SKU :

3117/10

product name :

Miglustat hydrochloride

description :

-glucosidase I and II inhibitor; also inhibits ceramide-specific glycosyltransferases and exhibits broad spectrum antiviral activity

target :

Glycosylase Inhibitors

category :

Small Molecules

unit size :

10 mg

observed molecular weight :

255.74

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Orally active -glucosidase I and II and ceramide-specific glycosyltransferase inhibitor. Rescues trafficking-deficient F508del-CFTR in human airway epithelial cells via inhibition of ER -glucosidases I and II. Also has broad spectrum antiviral activity. . Deuterated analog also available.

catalog number base :

3117

product keywords :

-glucosidase alpha-glucosidase I II inhibits inhibitors ceramide-specific glycosyltransferases Glycosylases Carbohydrate Metabolism NBDNJ N-Butyldeoxynojirimycin hydrochloride NB-DNJ Other Transferases Glycosylases Non-selective Antivirals 3117,

extended description :

-glucosidase I and II inhibitor; also inhibits ceramide-specific glycosyltransferases and exhibits broad spectrum antiviral activity

chemical name text :

(2R,3R,4R,5S)-1-Butyl-2-(hydroxymethyl)-3,4,5-piperidinetriol hydrochloride

formula :

C 10 H 21 NO 4 .HCl

formula text :

C10H21NO4.HCl

cas num :

210110-90-0

2020 USD :

218

2021 USD :

227 USD

alt names :

N -Butyldeoxynojirimycin hydrochloride, NB-DNJ

storage :

Desiccate at -20°C

more info or order :

Tocris Bioscience product webpage