product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
Miglustat hydrochloride
catalog :
3117/10
quantity :
10 mg
price :
286 USD
more info or order :
citations: 1
Reference
Huang W, Tsai C, Chen C, Chen T, Chen Y, Lin Y, et al. Glucosylceramide synthase inhibitor PDMP sensitizes chronic myeloid leukemia T315I mutant to Bcr-Abl inhibitor and cooperatively induces glycogen synthase kinase-3-regulated apoptosis. FASEB J. 2011;25:3661-73 pubmed publisher
product information
brand :
Tocris, a Bio-Techne brand
catalog number base :
3117
SKU :
3117/10
product name :
Miglustat hydrochloride
description :
-glucosidase I and II inhibitor; also inhibits ceramide-specific glycosyltransferases and exhibits broad spectrum antiviral activity
target :
Glycosylase Inhibitors
unit size :
10 mg
category :
Small Molecules
storage :
Desiccate at -20°C
observed molecular weight :
255.74
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Miglustat hydrochloride is an orally active -glucosidase I and II and ceramide-specific glycosyltransferase inhibitor. Rescues trafficking-deficient F508del-CFTR in human airway epithelial cells via inhibition of ER -glucosidases I and II. Also has broad spectrum antiviral activity.
product keywords :
-glucosidase alpha-glucosidase I II inhibits inhibitors ceramide-specific glycosyltransferases Glycosylases Carbohydrate Metabolism NBDNJ N-Butyldeoxynojirimycin hydrochloride NB-DNJ Other Transferases Glycosylases Non-selective Antivirals 3117,
extended description :
-glucosidase I and II inhibitor; also inhibits ceramide-specific glycosyltransferases and exhibits broad spectrum antiviral activity
chemical name text :
(2R,3R,4R,5S)-1-Butyl-2-(hydroxymethyl)-3,4,5-piperidinetriol hydrochloride
formula :
C10H21NO4.HCl
formula text :
C10H21NO4.HCl
cas num :
210110-90-0
USD :
283
USD 2025 :
286 USD
product details :
-glucosidase I and II inhibitor; also inhibits ceramide-specific glycosyltransferases and exhibits broad spectrum antiviral activity
alt names :
N -Butyldeoxynojirimycin hydrochloride,NB-DNJ
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK