WHI-P 154 | Tocris Bioscience 3115 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

WHI-P 154

catalog :

3115

quantity :

25 mg

price :

276 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

3115

SKU :

3115/25

product name :

WHI-P 154

description :

JAK3 kinase inhibitor. Also inhibits EGFR

target :

JAK Kinase Inhibitors

category :

Small Molecules

unit size :

25 mg

purity :

99%

observed molecular weight :

376.2

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

JAK3 inhibitor (IC50 = 1.8 M) that displays no activity at JAK1 or JAK2. Inhibits STAT1 activation, iNOS expression and NO production in macrophages in vitro . Also inhibits other common kinases including EGFR (IC50 = 4 nM), Src, Abl, VEGFR, MAPK and PI 3-K and induces apoptosis in human glioblastoma cell lines (IC50 = 158 M). Induces differentiation of neural progenitor cells.

catalog number base :

3115

product keywords :

JAK3 kinases inhibitors inhibits EGFR Potent Janus Activated Kinases Epidermal Growth Factor Receptors ErbB Her Receptor Tyrosine RTKs WHIP154 JAK Kinase EGFR Neural Stem Cells 3115,

extended description :

JAK3 kinase inhibitor. Also inhibits EGFR

chemical name text :

2-Bromo-4-[(6,7-dimethoxy-4-quinazolinyl)amino]phenol

formula :

C 16 H 14 BrN 3 O 3

formula text :

C16H14BrN3O3

cas num :

211555-04-3

2020 USD :

306

2021 USD :

276 USD

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage