Troglitazone | Tocris Bioscience 3114 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Troglitazone

catalog :

3114

quantity :

10 mg (also 50 mg)

price :

151 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Ross F, Hawley S, Auciello F, Gowans G, Atrih A, Lamont D, et al. Mechanisms of Paradoxical Activation of AMPK by the Kinase Inhibitors SU6656 and Sorafenib. Cell Chem Biol. 2017;24:813-824.e4 pubmed publisher
Bisikirska B, Bansal M, Shen Y, Teruya Feldstein J, Chaganti R, Califano A. Elucidation and Pharmacological Targeting of Novel Molecular Drivers of Follicular Lymphoma Progression. Cancer Res. 2016;76:664-74 pubmed publisher
Hegde V, Singh U, Nagarkatti P, Nagarkatti M. Critical Role of Mast Cells and Peroxisome Proliferator-Activated Receptor Î³ in the Induction of Myeloid-Derived Suppressor Cells by Marijuana Cannabidiol In Vivo. J Immunol. 2015;194:5211-22 pubmed publisher

product information

brand :

Tocris

master code :

3114

SKU :

3114/10

product name :

Troglitazone

description :

Selective PPAR agonist; antidiabetic agent

target :

PPAR gamma Receptor Agonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

97%

observed molecular weight :

441.54

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Selective PPAR receptor agonist (EC50 values are 780 and 555 nM at murine and human PPAR receptors respectively). Displays no activity at PPAR or PPAR receptors. Antidiabetic agent; exerts potent glucose-lowering effects in insulin-resistant diabetic mice. Displays anti-invasive effect on human breast cancer cells; reduces migration, adhesion and spreading on fibronectin-coated plates. Also inhibits cell growth of hematopoietic cell lines. Inhibits lamellipodia formation and actin polymerization.

catalog number base :

3114

product keywords :

Selective PPAR PPARgamma agonists antidiabetic agent Peroxisome Proliferator-activating Receptors Rezulin PPARgamma Receptors Stem Cell Proliferation 3114,

extended description :

Selective PPAR agonist; antidiabetic agent

chemical name text :

5-[[4-[(3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-yl)methoxy]phenyl]methyl]-2,4-thiazolidinedione

formula :

C 24 H 27 NO 5 S

formula text :

C24H27NO5S

cas num :

97322-87-7

2020 USD :

145

2021 USD :

151 USD

alt names :

Rezulin

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage