HU 308 | Tocris Bioscience 3088/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

HU 308

catalog :

3088/10

quantity :

10 mg (also 50 mg)

price :

362 USD

more info or order :

Tocris Bioscience product webpage

citations: 9

Reference
Sheng W, Chauhan P, Hu S, Prasad S, Lokensgard J. Antiallodynic Effects of Cannabinoid Receptor 2 (CB2R) Agonists on Retrovirus Infection-Induced Neuropathic Pain. Pain Res Manag. 2019;2019:1260353 pubmed publisher
Acevedo Canabal A, Colón Cruz L, Rodriguez Morales R, Varshney G, Burgess S, González Sepúlveda L, et al. Altered Swimming Behaviors in Zebrafish Larvae Lacking Cannabinoid Receptor 2. Cannabis Cannabinoid Res. 2019;4:88-101 pubmed publisher
Ke P, Shao B, Xu Z, Wei W, Han B, Chen X, et al. Activation of Cannabinoid Receptor 2 Ameliorates DSS-Induced Colitis through Inhibiting NLRP3 Inflammasome in Macrophages. PLoS ONE. 2016;11:e0155076 pubmed publisher
Schmitz K, Mangels N, H xe4 ussler A, Ferreir xf3 s N, Fleming I, Tegeder I. Pro-inflammatory obesity in aged cannabinoid-2 receptor-deficient mice. Int J Obes (Lond). 2016;40:366-79 pubmed publisher
Presley C, Abidi A, Suryawanshi S, Mustafa S, Meibohm B, Moore B. Preclinical evaluation of SMM-189, a cannabinoid receptor 2-specific inverse agonist. Pharmacol Res Perspect. 2015;3:e00159 pubmed publisher
Gianella Borradori M, Christou I, Bataille C, Cross R, Wynne G, Greaves D, et al. Ligand-based virtual screening identifies a family of selective cannabinoid receptor 2 agonists. Bioorg Med Chem. 2015;23:241-63 pubmed publisher
Sardinha J, Kelly M, Zhou J, Lehmann C. Experimental cannabinoid 2 receptor-mediated immune modulation in sepsis. Mediators Inflamm. 2014;2014:978678 pubmed publisher
Wilhelmsen K, Khakpour S, Tran A, Sheehan K, Schumacher M, Xu F, et al. The endocannabinoid/endovanilloid N-arachidonoyl dopamine (NADA) and synthetic cannabinoid WIN55,212-2 abate the inflammatory activation of human endothelial cells. J Biol Chem. 2014;289:13079-100 pubmed publisher
Solbrig M, Fan Y, Hazelton P. Prospects for cannabinoid therapies in viral encephalitis. Brain Res. 2013;1537:273-82 pubmed publisher

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

3088

SKU :

3088/10

product name :

HU 308

description :

Potent and selective CB2 agonist

target :

Cannabinoid R2/CB2 Agonists

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

98%

storage :

Store at -20°C

observed molecular weight :

414.62

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

HU 308 is a potent and selective CB2 receptor agonist (Ki values are 22.7 nM and 10 M for CB2 and CB1 receptors respectively, EC50 = 5.57 nM). Displays antiallodynic activity in the rat hindpaw incision model of postoperative pain. Also neuroprotective and improves motor performance in a mouse model of Huntington s Disease.

product keywords :

Potent selective CB2 agonists cannabinoids Receptors HU308 cb2r huntingtons disease CB2 Receptors 3088,

extended description :

Potent and selective CB2 agonist

chemical name text :

(1S,4S,5S)-4-[4-(1,1-Dimethylheptyl)-2,6-dimethoxyphenyl]-6,6-dimethylbicyclo[3.1.1]hept-2-ene-2-methanol

formula :

C27H42O3

formula text :

C27H42O3

cas num :

256934-39-1

USD :

358

USD 2025 :

362 USD

product details :

Potent and selective CB2 agonist

more info or order :

Tocris Bioscience product webpage