product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
Tempol
catalog :
3082/100
quantity :
100 mg
price :
79 USD
more info or order :
citations: 11
Reference
Rastogi S, Ellinwood S, Augenstreich J, Mayer Barber K, Briken V. Mycobacterium tuberculosis inhibits the NLRP3 inflammasome activation via its phosphokinase PknF. PLoS Pathog. 2021;17:e1009712 pubmed publisher
Hood K, Montezano A, Harvey A, Nilsen M, MacLean M, Touyz R. Nicotinamide Adenine Dinucleotide Phosphate Oxidase-Mediated Redox Signaling and Vascular Remodeling by 16?-Hydroxyestrone in Human Pulmonary Artery Cells: Implications in Pulmonary Arterial Hypertension. Hypertension. 2016;68:796-808 pubmed publisher
Somanna N, Valente A, Krenz M, Fay W, Delafontaine P, Chandrasekar B. The Nox1/4 Dual Inhibitor GKT137831 or Nox4 Knockdown Inhibits Angiotensin-II-Induced Adult Mouse Cardiac Fibroblast Proliferation and Migration. AT1 Physically Associates With Nox4. J Cell Physiol. 2016;231:1130-41 pubmed publisher
Beggs K, Maiuri A, Fullerton A, Poulsen K, Breier A, Ganey P, et al. Trovafloxacin-induced replication stress sensitizes HepG2 cells to tumor necrosis factor-alpha-induced cytotoxicity mediated by extracellular signal-regulated kinase and ataxia telangiectasia and Rad3-related. Toxicology. 2015;331:35-46 pubmed publisher
Tomasovic A, Kurrle N, Sürün D, Heidler J, Husnjak K, Poser I, et al. Sestrin 2 protein regulates platelet-derived growth factor receptor β (Pdgfrβ) expression by modulating proteasomal and Nrf2 transcription factor functions. J Biol Chem. 2015;290:9738-52 pubmed publisher
Senturk S, Yao Z, Camiolo M, Stiles B, Rathod T, Walsh A, et al. p53? is a transcriptionally inactive p53 isoform able to reprogram cells toward a metastatic-like state. Proc Natl Acad Sci U S A. 2014;111:E3287-96 pubmed publisher
Meyer M, Fredette N, Barton M, Prossnitz E. Regulation of vascular smooth muscle tone by adipose-derived contracting factor. PLoS ONE. 2013;8:e79245 pubmed publisher
Nesuashvili L, Hadley S, Bahia P, Taylor Clark T. Sensory nerve terminal mitochondrial dysfunction activates airway sensory nerves via transient receptor potential (TRP) channels. Mol Pharmacol. 2013;83:1007-19 pubmed publisher
Lowry J, Brovkovych V, Zhang Y, Skidgel R. Endothelial nitric-oxide synthase activation generates an inducible nitric-oxide synthase-like output of nitric oxide in inflamed endothelium. J Biol Chem. 2013;288:4174-93 pubmed publisher
Valente A, Yoshida T, Murthy S, Sakamuri S, Katsuyama M, Clark R, et al. Angiotensin II enhances AT1-Nox1 binding and stimulates arterial smooth muscle cell migration and proliferation through AT1, Nox1, and interleukin-18. Am J Physiol Heart Circ Physiol. 2012;303:H282-96 pubmed publisher
Ruparel S, Henry M, AKOPIAN A, Patil M, Zeldin D, Roman L, et al. Plasticity of cytochrome P450 isozyme expression in rat trigeminal ganglia neurons during inflammation. Pain. 2012;153:2031-9 pubmed publisher
product information
brand :
Tocris, a Bio-Techne brand
catalog number base :
3082
SKU :
3082/100
product name :
Tempol
description :
Superoxide scavenger; antioxidant
target :
Additional Antioxidant Compounds
unit size :
100 mg
category :
Small Molecules
purity :
99%
storage :
Store at -20°C
observed molecular weight :
172.24
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Tempol is a superoxide scavenger that displays neuroprotective, anti-inflammatory and analgesic effects. Tempol reduces -radiation-induced damage in hematopoietic stem cells in vitro and in vivo .
product keywords :
Superoxide scavenger antioxidant hematopoietic haematopoietic stem cells HSC Antioxidants Hematopoietic Stem Cells 3082,
extended description :
Superoxide scavenger; antioxidant
chemical name text :
1-Oxyl-2,2,6,6-tetramethyl-4-hydroxypiperidine
formula :
C9H18NO2
formula text :
C9H18NO2
cas num :
2226-96-2
USD :
78
USD 2025 :
79 USD
product details :
Superoxide scavenger; antioxidant
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK