product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
Nafamostat mesylate
catalog :
3081/10
quantity :
10 mg (also 50 mg)
price :
127 USD
more info or order :
citations: 1
Reference
Scott I, Majithiya J, Sandén C, Thornton P, Sanders P, Moore T, et al. Interleukin-33 is activated by allergen- and necrosis-associated proteolytic activities to regulate its alarmin activity during epithelial damage. Sci Rep. 2018;8:3363 pubmed publisher
image
image 1 :
Tocris Bioscience 3081/10 image 1
Cat.No. 3081 - Nafamostat mesylate C19H17N5O2.2CH4O3S CAS No. 82956-11-4
product information
brand :
Tocris
MasterCode :
3081
SKU :
3081/10
product name :
Nafamostat mesylate
target :
TMPRSS2 Inhibitors
category :
Small Molecules
unit size :
10 mg (also 50 mg)
purity :
99%
observed molecular weight :
539.59
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Nafamostat mesylate is a broad spectrum serine protease inhibitor. Displays selectivity for human tryptase when used at relatively low concentrations. Reduces eosinophil infiltration, mast cell activation and airway responsiveness in a murine model of asthma. Inhibits SARS-CoV-2 infection in vitro (EC50 = 22.50 M). . Tocris products are for biomedical research use only. They are not intended for human or veterinary use.
extended description :
Serine protease inhibitor; inhibits tryptase
chemical name text :
4-[(Aminoiminomethyl)amino]benzoic acid 6-(aminoiminomethyl)-2-naphthalenyl ester dimethanesulfonate
formula :
C 19 H 17 N 5 O 2 .2CH 4 O 3 S
formula text :
C19H17N5O2.2CH4O3S
cas num :
82956-11-4
USD :
127 USD
product details :
Serine protease inhibitor; inhibits tryptase
storage :
Store at +4°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK