product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
Desipramine hydrochloride
catalog :
3067
quantity :
50 mg
price :
87 USD
more info or order :
citations: 8
Reference
Tanaka M, Sun F, Li Y, Mooney R. A mesocortical dopamine circuit enables the cultural transmission of vocal behaviour. Nature. 2018;563:117-120 pubmed publisher
Kramer D, Risso D, Kosillo P, Ngai J, Bateup H. Combinatorial Expression of Grp and Neurod6 Defines Dopamine Neuron Populations with Distinct Projection Patterns and Disease Vulnerability. Eneuro. 2018;5: pubmed publisher
Chou D, Peng H, Lin T, Lai C, Hsieh M, Wen Y, et al. (2R,6R)-hydroxynorketamine rescues chronic stress-induced depression-like behavior through its actions in the midbrain periaqueductal gray. Neuropharmacology. 2018;139:1-12 pubmed publisher
LaRocca T, Stivison E, Mal Sarkar T, Hooven T, Hod E, Spitalnik S, et al. CD59 signaling and membrane pores drive Syk-dependent erythrocyte necroptosis. Cell Death Dis. 2015;6:e1773 pubmed publisher
Czysz A, Schappi J, Rasenick M. Lateral diffusion of Gαs in the plasma membrane is decreased after chronic but not acute antidepressant treatment: role of lipid raft and non-raft membrane microdomains. Neuropsychopharmacology. 2015;40:766-73 pubmed publisher
Yuen E, Qin L, Wei J, Liu W, Liu A, Yan Z. Synergistic regulation of glutamatergic transmission by serotonin and norepinephrine reuptake inhibitors in prefrontal cortical neurons. J Biol Chem. 2014;289:25177-85 pubmed publisher
Bucher E, Fox M, Kim L, Kirkpatrick D, Rodeberg N, Belle A, et al. Medullary norepinephrine neurons modulate local oxygen concentrations in the bed nucleus of the stria terminalis. J Cereb Blood Flow Metab. 2014;34:1128-37 pubmed publisher
Choi S, Chung S, Cho J, Cho Y, Kim J, Kim J, et al. Changes in c-Fos Expression in the Forced Swimming Test: Common and Distinct Modulation in Rat Brain by Desipramine and Citalopram. Korean J Physiol Pharmacol. 2013;17:321-9 pubmed publisher
product information
brand :
Tocris
master code :
3067
SKU :
3067/50
product name :
Desipramine hydrochloride
description :
Selective inhibitor of noradrenalin transporters
target :
Adrenergic Transporter Inhibitors
category :
Small Molecules
unit size :
50 mg
purity :
99%
observed molecular weight :
302.84
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Tricyclic antidepressant that is a selective inhibitor of noradrenalin transporters (Ki values are 4, 61 and 78720 nM for NET, SERT and DAT transporters respectively).
catalog number base :
3067
product keywords :
Selective inhibitors inhibits noradrenaline transporters Transporter NET Adrenergic Monoamine Neurotransmitter Adrenergic Transporters 3067,
extended description :
Selective inhibitor of noradrenalin transporters
chemical name text :
10-11-Dihydro-N-methyl-5H-dibenz(Z)[b,f]azepine-5-propanamine hydrochloride
formula :
C 18 H 22 N 2 .HCl
formula text :
C18H22N2.HCl
cas num :
58-28-6
2020 USD :
83
2021 USD :
87 USD
storage :
Desiccate at +4°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK