NS 1643 | Tocris Bioscience 3062 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

NS 1643

catalog :

3062

quantity :

10 mg (also 50 mg)

price :

149 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Perissinotti L, Guo J, De Biase P, Clancy C, Duff H, Noskov S. Kinetic model for NS1643 drug activation of WT and L529I variants of Kv11.1 (hERG1) potassium channel. Biophys J. 2015;108:1414-1424 pubmed publisher

product information

brand :

Tocris

master code :

3062

SKU :

3062/10

product name :

NS 1643

description :

KV11.1 (hERG) channel activator; antiarrhythmic

target :

Voltage-gated Potassium Channel Activators

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

380.24

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Human ether-a-go-go related gene (hERG) KV11.1 channel activator (EC50 = 10.5 M). Exhibits different molecular mechanisms of action at KV11.1 (hERG1) and KV11.2 (hERG2) channels. Displays antiarrhythmic activity in vitro .

catalog number base :

3062

product keywords :

hERG channel activators Antiarrhythmic Potassium KV Channels Human Ether-A-Go-Go Gene voltage-gated voltage-dependent K+ NS1643 Voltage-Gated Potassium Channels 3062,

extended description :

KV11.1 (hERG) channel activator; antiarrhythmic

chemical name text :

N,N -Bis[2-hydroxy-5-(trifluoromethyl)phenyl]urea

formula :

C 15 H 10 F 6 N 2 O 3

formula text :

C15H10F6N2O3

cas num :

448895-37-2

2020 USD :

144

2021 USD :

149 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage