NS 1643 | Tocris Bioscience 3062/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

NS 1643

catalog :

3062/10

quantity :

10 mg (also 50 mg)

price :

186 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Perissinotti L, Guo J, De Biase P, Clancy C, Duff H, Noskov S. Kinetic model for NS1643 drug activation of WT and L529I variants of Kv11.1 (hERG1) potassium channel. Biophys J. 2015;108:1414-1424 pubmed publisher

image

image 1 :

Cat.No. 3062 - NS 1643 C15H10F6N2O3 CAS No. 448895-37-2

product information

brand :

Tocris

MasterCode :

3062

SKU :

3062/10

product name :

NS 1643

target :

Voltage-gated Potassium Channel Activators

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

380.24

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

NS 1643 is a human ether-a-go-go related gene (hERG) KV11.1 channel activator (EC50 = 10.5 M). Exhibits different molecular mechanisms of action at KV11.1 (hERG1) and KV11.2 (hERG2) channels. Displays antiarrhythmic activity in vitro .

extended description :

KV11.1 (hERG) channel activator; antiarrhythmic

chemical name text :

N,N -Bis[2-hydroxy-5-(trifluoromethyl)phenyl]urea

formula :

C 15 H 10 F 6 N 2 O 3

formula text :

C15H10F6N2O3

cas num :

448895-37-2

USD :

186 USD

product details :

KV11.1 (hERG) channel activator; antiarrhythmic

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage