product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
Pentoxifylline
catalog :
3056/50
quantity :
50 mg
price :
50 USD
more info or order :
citations: 18
Reference
Wang W, Li C, Chen Q, van der Goes M, Hawrot J, Yao A, et al. Striatopallidal dysfunction underlies repetitive behavior in Shank3-deficient model of autism. J Clin Invest. 2017;127:1978-1990 pubmed publisher
Park C. Maresin 1 Inhibits TRPV1 in Temporomandibular Joint-Related Trigeminal Nociceptive Neurons and TMJ Inflammation-Induced Synaptic Plasticity in the Trigeminal Nucleus. Mediators Inflamm. 2015;2015:275126 pubmed publisher
Liu Z, Chen J, Mirando A, Wang C, Zuscik M, O Keefe R, et al. A dual role for NOTCH signaling in joint cartilage maintenance and osteoarthritis. Sci Signal. 2015;8:ra71 pubmed publisher
Zhang W, Xu C, Tu H, Wang Y, Sun Q, Hu P, et al. GABAB receptor upregulates fragile X mental retardation protein expression in neurons. Sci Rep. 2015;5:10468 pubmed publisher
Malyshev A, Goz R, LoTurco J, Volgushev M. Advantages and limitations of the use of optogenetic approach in studying fast-scale spike encoding. PLoS ONE. 2015;10:e0122286 pubmed publisher
Guidi M, Kumar A, Foster T. Impaired attention and synaptic senescence of the prefrontal cortex involves redox regulation of NMDA receptors. J Neurosci. 2015;35:3966-77 pubmed publisher
Feng B, Zhu Y, La J, Wills Z, Gebhart G. Experimental and computational evidence for an essential role of NaV1.6 in spike initiation at stretch-sensitive colorectal afferent endings. J Neurophysiol. 2015;113:2618-34 pubmed publisher
Wang Y, Yuan J, Qian Z, Zhang X, Chen Y, Hou X, et al. β2 adrenergic receptor activation governs cardiac repolarization and arrhythmogenesis in a guinea pig model of heart failure. Sci Rep. 2015;5:7681 pubmed publisher
Thueson L, Emmons T, Browning D, Kreitinger J, Shepherd D, Wetzel S. In vitro exposure to the herbicide atrazine inhibits T cell activation, proliferation, and cytokine production and significantly increases the frequency of Foxp3+ regulatory T cells. Toxicol Sci. 2015;143:418-29 pubmed publisher
Simonson B, Morani A, Ewald A, Walker L, Kumar N, Simpson D, et al. Pharmacology and anti-addiction effects of the novel ? opioid receptor agonist Mesyl Sal B, a potent and long-acting analogue of salvinorin A. Br J Pharmacol. 2015;172:515-31 pubmed publisher
Kumar A, Foster T. Linking redox regulation of NMDAR synaptic function to cognitive decline during aging. J Neurosci. 2013;33:15710-5 pubmed publisher
Bailes H, Zhuang L, Lucas R. Reproducible and sustained regulation of G?s signalling using a metazoan opsin as an optogenetic tool. PLoS ONE. 2012;7:e30774 pubmed publisher
Zhang Z, Jiao Y, Sun Q. Developmental maturation of excitation and inhibition balance in principal neurons across four layers of somatosensory cortex. Neuroscience. 2011;174:10-25 pubmed publisher
Zhang Z, Sun Q. Development of NMDA NR2 subunits and their roles in critical period maturation of neocortical GABAergic interneurons. Dev Neurobiol. 2011;71:221-45 pubmed publisher
Zhao W, Zhang M, Miao Y, Yang X, Wang Z. Melatonin potentiates glycine currents through a PLC/PKC signalling pathway in rat retinal ganglion cells. J Physiol. 2010;588:2605-19 pubmed publisher
Penzo M, Pena J. Endocannabinoid-mediated long-term depression in the avian midbrain expressed presynaptically and postsynaptically. J Neurosci. 2009;29:4131-9 pubmed publisher
Jakubs K, Nanobashvili A, Bonde S, Ekdahl C, Kokaia Z, Kokaia M, et al. Environment matters: synaptic properties of neurons born in the epileptic adult brain develop to reduce excitability. Neuron. 2006;52:1047-59 pubmed
Pierre S, Häusler J, Birod K, Geisslinger G, Scholich K. PAM mediates sustained inhibition of cAMP signaling by sphingosine-1-phosphate. EMBO J. 2004;23:3031-40 pubmed
product information
brand :
Tocris
SKU :
3056/50
product name :
Pentoxifylline
unit sizes :
50 mg
description :
PDE inhibitor
target :
Phosphodiesterase Inhibitors
category :
Small Molecules
purity :
99%
observed molecular weight :
278.31
details of functionality :
Phosphodiesterase inhibitor that blocks production of TNF- and other cytokines. Displays antinociceptive activity.
catalog number base :
3056
extended description :
PDE inhibitor
chemical name text :
3,7-Dimethyl-1-(5-oxohexyl)xanthine
formula :
C 13 H 18 N 4 O 3
formula text :
C13H18N4O3
cas num :
5/6/93
USD :
50 USD
product details :
PDE inhibitor
alt names :
PTX
storage :
Store at RT
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK