CP 809101 hydrochloride | Tocris Bioscience 3041/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

CP 809101 hydrochloride

catalog :

3041/10

quantity :

10 mg (also 50 mg)

price :

210 USD

more info or order :

Tocris Bioscience product webpage

citations: 6

Reference
Yamamoto H, Kamegaya E, Hagino Y, Takamatsu Y, Sawada W, Matsuzawa M, et al. Loss of GluN2D subunit results in social recognition deficit, social stress, 5-HT2C receptor dysfunction, and anhedonia in mice. Neuropharmacology. 2017;112:188-197 pubmed publisher
Gerhold K, Drdla Schutting R, Honsek S, Forsthuber L, SandkÃ¼hler J. Pronociceptive and Antinociceptive Effects of Buprenorphine in the Spinal Cord Dorsal Horn Cover a Dose Range of Four Orders of Magnitude. J Neurosci. 2015;35:9580-94 pubmed publisher
Goda S, Piasecka J, Olszewski M, Kasicki S, Hunt M. Serotonergic hallucinogens differentially modify gamma and high frequency oscillations in the rat nucleus accumbens. Psychopharmacology (Berl). 2013;228:271-82 pubmed publisher
Greenwood B, Strong P, Loughridge A, Day H, Clark P, Mika A, et al. 5-HT2C receptors in the basolateral amygdala and dorsal striatum are a novel target for the anxiolytic and antidepressant effects of exercise. PLoS ONE. 2012;7:e46118 pubmed publisher
Austgen J, Dantzler H, Barger B, Kline D. 5-hydroxytryptamine 2C receptors tonically augment synaptic currents in the nucleus tractus solitarii. J Neurophysiol. 2012;108:2292-305 pubmed publisher
Schulz S, Heidmann K, Mike A, Klaft Z, Heinemann U, Gerevich Z. First and second generation antipsychotics influence hippocampal gamma oscillations by interactions with 5-HT3 and D3 receptors. Br J Pharmacol. 2012;167:1480-91 pubmed publisher

product information

brand :

Tocris

catalog number base :

3041

SKU :

3041/10

product name :

CP 809101 hydrochloride

units size :

10 mg (also 50 mg)

description :

Potent and selective 5-HT2C agonist

target :

5-HT2C Receptor Agonists

category :

Small Molecules

purity :

99%

observed molecular weight :

341.24

url print :

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details of functionality :

CP 809101 hydrochloride is a potent and selective 5-HT2C receptor agonist (pEC50 values are 9.96, 7.19 and 6.81 for human 5-HT2C, 5-HT2B and 5-HT2A receptors respectively). Displays antipsychotic activity; suppresses condition avoidance responding (CAR) and inhibits PCP and amphetamine-stimulated hyperactivity in rats following subcutaneous administration.

top caption :

Potent and selective 5-HT2C agonist

extended description :

Potent and selective 5-HT2C agonist

chemical name text :

2-[(3-Chlorophenyl)methoxy]-6-(1-piperazinyl)pyrazine hydrochloride

formula :

C15H17N4OCl.HCl

formula text :

C15H17N4OCl.HCl

cas num :

1215721-40-6

USD :

210 USD

product details :

Potent and selective 5-HT2C agonist

storage :

Desiccate at RT

more info or order :

Tocris Bioscience product webpage