TCS 2312 | Tocris Bioscience 3038 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

TCS 2312

catalog :

3038

quantity :

1 mg

price :

221 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Davari K, Frankenberger S, Schmidt A, Tomi N, Jungnickel B. Checkpoint kinase 2 is required for efficient immunoglobulin diversification. Cell Cycle. 2014;13:3659-69 pubmed publisher
Frankenberger S, Davari K, Fischer Burkart S, Böttcher K, Tomi N, Zimber Strobl U, et al. Checkpoint kinase 1 negatively regulates somatic hypermutation. Nucleic Acids Res. 2014;42:3666-74 pubmed publisher

product information

brand :

Tocris

master code :

3038

SKU :

3038/1

product name :

TCS 2312

description :

Potent Chk1 inhibitor

target :

Checkpoint Kinase Inhibitors

category :

Small Molecules

unit size :

1 mg

purity :

97%

observed molecular weight :

412.48

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective checkpoint kinase 1 (chk1) inhibitor (Ki = 0.38 nM, EC50 = 60 nM). Enhances the cell killing activity of Gemcitabine (Cat. No. 3259) in breast and prostate cancer cell lines and displays antiproliferative effects in vitro .

catalog number base :

3038

product keywords :

Potent Chk1 inhibitors inhibits Checkpoint Kinases Control TCS2312 Checkpoint Kinases Checkpoint Control Kinases 3038,

extended description :

Potent Chk1 inhibitor

chemical name text :

4 -[5-[[3-[(Cyclopropylamino)methyl]phenyl]amino]-1H-pyrazol-3-yl]-[1,1 -biphenyl]-2,4-diol

formula :

C 25 H 24 N 4 O 2

formula text :

C25H24N4O2

cas num :

838823-31-7

2020 USD :

212

2021 USD :

221 USD

storage :

Store at -80°C

more info or order :

Tocris Bioscience product webpage