TCS 2312 | Tocris Bioscience 3038/1 product information

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product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

TCS 2312

catalog :

3038/1

quantity :

1 mg

price :

243 USD

citations: 2

Reference
Davari K, Frankenberger S, Schmidt A, Tomi N, Jungnickel B. Checkpoint kinase 2 is required for efficient immunoglobulin diversification. Cell Cycle. 2014;13:3659-69 pubmed publisher
Frankenberger S, Davari K, Fischer Burkart S, Böttcher K, Tomi N, Zimber Strobl U, et al. Checkpoint kinase 1 negatively regulates somatic hypermutation. Nucleic Acids Res. 2014;42:3666-74 pubmed publisher

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

3038

SKU :

3038/1

product name :

TCS 2312

description :

Potent Chk1 inhibitor

target :

Checkpoint Kinase Inhibitors

unit size :

1 mg

category :

Small Molecules

purity :

97%

storage :

Store at -80°C

observed molecular weight :

412.48

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

TCS 2312 is a potent and selective checkpoint kinase 1 (chk1) inhibitor (Ki = 0.38 nM, EC50 = 60 nM). Enhances the cell killing activity of Gemcitabine (Cat. No. 3259) in breast and prostate cancer cell lines and displays antiproliferative effects in vitro .

product keywords :

Potent Chk1 inhibitors inhibits Checkpoint Kinases Control TCS2312 Checkpoint Kinases Checkpoint Control Kinases 3038,

extended description :

Potent Chk1 inhibitor

chemical name text :

4 -[5-[[3-[(Cyclopropylamino)methyl]phenyl]amino]-1H-pyrazol-3-yl]-[1,1 -biphenyl]-2,4-diol

formula :

C25H24N4O2

formula text :

C25H24N4O2

cas num :

838823-31-7

USD :

270

USD 2025 :

243 USD

product details :

Potent Chk1 inhibitor