product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
Gastrin I (human)
catalog :
3006/1
quantity :
1 mg
price :
442 USD
more info or order :
citations: 10
Reference
Dings M, van der Zalm A, Bootsma S, van Maanen T, Waasdorp C, van den Ende T, et al. Estrogen-related receptor alpha drives mitochondrial biogenesis and resistance to neoadjuvant chemoradiation in esophageal cancer. Cell Rep Med. 2022;3:100802 pubmed publisher
He G, Lin L, DeMartino J, Zheng X, Staliarova N, Dayton T, et al. Optimized human intestinal organoid model reveals interleukin-22-dependency of paneth cell formation. Cell Stem Cell. 2022;29:1333-1345.e6 pubmed publisher
Post Y, Puschhof J, Beumer J, Kerkkamp H, de Bakker M, Slagboom J, et al. Snake Venom Gland Organoids. Cell. 2020;180:233-247.e21 pubmed publisher
Filippini D, Agosto S, Delfino P, Simbolo M, Piro G, Rusev B, et al. Immunoevolution of mouse pancreatic organoid isografts from preinvasive to metastatic disease. Sci Rep. 2019;9:12286 pubmed publisher
Colomer C, Margalef P, Villanueva A, Vert A, Pecharroman I, Sole L, et al. IKKα Kinase Regulates the DNA Damage Response and Drives Chemo-resistance in Cancer. Mol Cell. 2019;75:669-682.e5 pubmed publisher
Capurro M, Greenfield L, Prashar A, Xia S, Abdullah M, Wong H, et al. VacA generates a protective intracellular reservoir for Helicobacter pylori that is eliminated by activation of the lysosomal calcium channel TRPML1. Nat Microbiol. 2019;: pubmed publisher
Kijima T, Nakagawa H, Shimonosono M, Chandramouleeswaran P, Hara T, Sahu V, et al. Three-Dimensional Organoids Reveal Therapy Resistance of Esophageal and Oropharyngeal Squamous Cell Carcinoma Cells. Cell Mol Gastroenterol Hepatol. 2019;7:73-91 pubmed publisher
Somerville T, Xu Y, Miyabayashi K, Tiriac H, Cleary C, Maia Silva D, et al. TP63-Mediated Enhancer Reprogramming Drives the Squamous Subtype of Pancreatic Ductal Adenocarcinoma. Cell Rep. 2018;25:1741-1755.e7 pubmed publisher
Roe J, Hwang C, Somerville T, Milazzo J, Lee E, Da Silva B, et al. Enhancer Reprogramming Promotes Pancreatic Cancer Metastasis. Cell. 2017;170:875-888.e20 pubmed publisher
Bartfeld S, Bayram T, van de Wetering M, Huch M, Begthel H, Kujala P, et al. In vitro expansion of human gastric epithelial stem cells and their responses to bacterial infection. Gastroenterology. 2015;148:126-136.e6 pubmed publisher
product information
brand :
Tocris, a Bio-Techne brand
catalog number base :
3006
SKU :
3006/1
product name :
Gastrin I (human)
description :
Selective CCK2 agonist
target :
CCK2 Receptor Agonists
unit size :
1 mg
category :
Peptides
purity :
95%
species :
Human
storage :
Store at -20°C
observed molecular weight :
2098.22
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=peptides
details of functionality :
Gastrin I (human) is an endogenous peptide produced in the stomach that acts as a selective CCK2 receptor agonist. Gastrin I stimulates gastric acid secretion and has a mitogenic effect on gastric cells. Gastrin I stimulates gastric epithelial cell proliferation and histamine secretion (EC50 values are 6.2 pM and 0.014 nM, respectively). Gastrin I is also used in the culture of stomach, intestine and pancreas organoids. For more information about using Gastrin I in the generation of gastric organoids see the Human Gastric Organoid Culture Protocol .
product keywords :
Selective CCK2 agonists Cholecystokinin2 Receptors GastrinI (human) organoids gastric histamine CCK2 Receptor Organoids 3006,
extended description :
Selective CCK2 agonist
formula :
C97H124N20O31S
formula text :
C97H124N20O31S
cas num :
10047-33-3
USD :
424
USD 2025 :
442 USD
product details :
Selective CCK2 agonist
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK