RWJ 67657 | Tocris Bioscience 2999 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

RWJ 67657

catalog :

2999

quantity :

10 mg

price :

194 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

2999

SKU :

2999/10

product name :

RWJ 67657

description :

Potent, selective p38 and p38 inhibitor

target :

p38 Inhibitors

category :

Small Molecules

unit size :

10 mg

purity :

98%

observed molecular weight :

425.5

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Selective p38 and p38 inhibitor (IC50 values are 1 and 11 u M respectively) that displays no activity at p38 , p38 and a range of other kinases. Potently inhibits TNF- and IL-1 release (IC50 values are 3 and 11 nM respectively) and suppresses HIV-1 replication in T cells in vitro . Displays cardioprotective and anti-inflammatory activity in vivo . Orally active.

catalog number base :

2999

product keywords :

Potent selective p38 p38alpha p38 p38beta inhibitors inhibits MAPK Signaling Signalling Mitogen-Activated Protein Kinases RWJ67657 p38 2999,

extended description :

Potent, selective p38 and p38 inhibitor

chemical name text :

4-[4-(4-Fluorophenyl)-1-(3-phenylpropyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]-3-butyn-1-ol

formula :

C 27 H 24 FN 3 O

formula text :

C27H24FN3O

cas num :

215303-72-3

2020 USD :

194

2021 USD :

194 USD

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage